Laboratory Studies of Disinfectants Against Legionella Pneumophila

Overview

Journal Appl Environ Microbiol

Specialties Environmental Health
Microbiology

Date 1980 Oct 1

PMID 6252840

Citations 26

Authors

P SKALIY

T A Thompson

G W GORMAN

G K Morris

H V McEachern

D C Mackel

Affiliations

Soon will be listed here.

Abstract

Legionella pneumophila suspended in tap water was exposed to biocides recommended for inhibiting biological growth in cooling towers and evaporative condensers of air-conditioning systems. Chlorine, 2,2-dibromo-3-nitrilopropionamide, and a compound containing didecyldimethylammonium chloride and isopropanol were effective in destroying concentratiois of 10(5) to 10(6) viable cells per ml. Formulations consisting of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, disodium ethylene bis(thiocarbamate) and sodium dimethyl dithiocarbamate, and a phenolic with pentachlorophenate and sodium salts of other chlorophenols were less effective.

Citing Articles

Rapid Testing and Interventions to Control Proliferation following a Legionnaires' Disease Outbreak Associated with Cooling Towers.

Young C, Smith D, Wafer T, Crook B Microorganisms. 2021; 9(3).

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Prior Exposure to Ortho-Phthalaldehyde Augments IgE-Mediated Immune Responses to Didecyldimethylammonium Chloride: Potential for 2 Commonly Used Antimicrobials to Synergistically Enhance Allergic Disease.

Shane H, Lukomska E, Weatherly L, Baur R, Anderson S Toxicol Sci. 2020; 178(1):127-137.

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Potential classification of chemical immunologic response based on gene expression profiles.

Anderson S, Baur R, Kashon M, Lukomska E, Weatherly L, Shane H J Immunotoxicol. 2020; 17(1):122-134.

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Evaluation of the irritancy and hypersensitivity potential following topical application of didecyldimethylammonium chloride.

Anderson S, Shane H, Long C, Lukomska E, Meade B, Marshall N J Immunotoxicol. 2016; 13(4):557-66.

PMID: 27216637 PMC: 4961531. DOI: 10.3109/1547691X.2016.1140854.

Limitations of Using Propidium Monoazide with qPCR to Discriminate between Live and Dead Legionella in Biofilm Samples.

Taylor M, Bentham R, Ross K Microbiol Insights. 2014; 7:15-24.

PMID: 25288885 PMC: 4167484. DOI: 10.4137/MBI.S17723.

References

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