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In Vitro Susceptibility of Gram-negative Bacilli from Pediatric Patients to Moxalactam, Cefotaxime, Ro 13-9904, and Other Cephalosporins

Overview
Journal Antimicrob Agents Chemother
Publisher American Society for Microbiology
Specialty Pharmacology
Date 1980 Sep 1
PMID 6252837
Citations 22
Authors
S Shelton
J D Nelson
G H McCracken Jr
Affiliations
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Abstract

Moxalactam, Ro 13-9904, cefotaxime, cefoperazone, older cephalosporins, and four aminoglycosides were tested in vitro against 432 strains of gram-negative bacteria isolated from pediatric patients. The new drugs were uniformly active against coliform bacilli obtained from patients with meningitis and against aminoglycoside-resistant coliform bacilli.

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Ceftriaxone. A review of its antibacterial activity, pharmacological properties and therapeutic use.

Richards D, Heel R, Brogden R, Speight T, Avery G Drugs. 1984; 27(6):469-527.

PMID: 6329638 DOI: 10.2165/00003495-198427060-00001.

The cephalosporin compounds in severe neonatal infection.

Schaad U Eur J Pediatr. 1984; 141(3):143-6.

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Once-daily administration of ceftriaxone in the treatment of meningitis and other serious infections in children.

Martin E Eur J Clin Microbiol. 1983; 2(5):509-15.

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The potential uses of ceftriaxone.

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References
1.
McCracken Jr G, Mize S . A controlled study of intrathecal antibiotic therapy in gram-negative enteric meningitis of infancy. Report of the neonatal meningitis cooperative study group. J Pediatr. 1976; 89(1):66-72. DOI: 10.1016/s0022-3476(76)80929-8. View
2.
Belohradsky B, Bruch K, Geiss D, Kafetzis D, Marget W, Peters G . Intravenous cefotaxime in children with bacterial meningitis. Lancet. 1980; 1(8159):61-3. DOI: 10.1016/s0140-6736(80)90491-2. View