Study of Biochemical and Hormonal Data in Idiopathic Scoliosis in Girls

Overview

Journal Arch Orthop Trauma Surg (1978)

Specialty Orthopedics

Date 1981 Jan 1

PMID 6170273

Citations 3

Authors

S Willner

O Johnell

Affiliations

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Abstract

Basic cause and factors determining the progression of idiopathic scoliosis are assumed to be multifarious. A deviating growth pattern has also been suspected. The influence of certain bone and growth-stimulating hormones and related biochemical values has been studied in girls with idiopathic scoliosis compared to controls. The mineral content (S-Ca, S-P and S-Alp) did not differ between idiopathic scoliosis and controls. a2-macroglobulin was slightly increased in the scoliotic group in all ages. Morning fast GH and Somatomedin A level in serum were also increased in the scoliotic group. Even a significant increase of 17-oxosteroids are metabolites of androgens in girls. 17-oxosteroids in urine mainly metabolites of cortisol, neither calcitonin or parathyroid hormone, in contrary, did not differ between scoliosis and controls.

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