Circadian Rhythm for Tryptophan Pyrrolase Activity and Its Circulating Substrate

Overview

Journal Science

Specialty Science

Date 1966 Sep 30

PMID 5917076

Citations 12

Authors

M I RAPOPORT

R D Feigin

J Bruton

W R Beisel

Affiliations

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Abstract

Hepatic tryptophan pyrrolase and its circulating substrate, whole blood tryptophan, have a circadian rhythmicity in mice. Intact adrenocortical function is required for the normal rhythmicity of both enzyme and substrate although an altered but less apparent rhythm persists in the adrenalectomized state.

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