» Articles » PMID: 590837

Stagnant Loop Syndrome in Patients with Continent Ileostomy (intra-abdominal Ileal Reservoir)

Overview
Journal Gut
Specialty Gastroenterology
Date 1977 Oct 1
PMID 590837
Citations 20
Authors
Affiliations
Soon will be listed here.
Abstract

Intestinal absorption and bacteriology of the ileal contents were compared in seven patients with continent ileostomy and seven patients with conventional ileostomy. The absorption of vitamin B12 was reduced in five patients with continent ileostomy and subnormal in two patients with conventional ileostomy. Steatorrhoea was present in four patients with continent and one patient with conventional ileostomy. Increased concentrations of total anaerobic bacteria and Bacteroides were found in the ileum of the patients with continent ileostomy. After an oral dose of (1-14C) glycocholic acid there was no difference in the faecal excretion of radioactivity, whereas the 14CO2-expiration was increased in two patients with continent ileostomy. In four patients with continent ileostomy and malabsorption of B12, there was evidence of a stagnant loopsyndrome as oral lincomycin treatment resulted in increased absorption of B12 decreased excretion of faecal fat, and decreased concentrations of Bacteroides in the ileum.

Citing Articles

Human gut capture vitamin B via cell surface-exposed lipoproteins.

Wexler A, Schofield W, Degnan P, Folta-Stogniew E, Barry N, Goodman A Elife. 2018; 7.

PMID: 30226189 PMC: 6143338. DOI: 10.7554/eLife.37138.


Serum biochemical evaluation of patients with functional pouches ten to 20 years after restorative proctocolectomy.

MKoma A Int J Colorectal Dis. 2006; 21(7):711-20.

PMID: 16437210 DOI: 10.1007/s00384-005-0076-3.


Should we monitor vitamin B12 levels in patients who have had end-ileostomy for inflammatory bowel disease?.

Jayaprakash A, Creed T, Stewart L, Colton B, Mountford R, Standen G Int J Colorectal Dis. 2003; 19(4):316-8.

PMID: 14618349 DOI: 10.1007/s00384-003-0556-2.


Pouchitis.

Schouten W Mediators Inflamm. 1998; 7(3):175-81.

PMID: 9705605 PMC: 1781844. DOI: 10.1080/09629359891117.


Fecal bile acids, short-chain fatty acids, and bacteria after ileal pouch-anal anastomosis do not differ in patients with pouchitis.

Sandborn W, Tremaine W, Batts K, Pemberton J, Rossi S, Hofmann A Dig Dis Sci. 1995; 40(7):1474-83.

PMID: 7628271 DOI: 10.1007/BF02285195.


References
1.
Fromm H, Hofmann A . Breath test for altered bile-acid metabolism. Lancet. 1971; 2(7725):621-5. DOI: 10.1016/s0140-6736(71)80068-5. View

2.
Brandberg A, KOCK N, Philipson B . Bacterial flora in intraabdominal ileostomy reservoir. A study of 23 patients provided with "continent ileostomy". Gastroenterology. 1972; 63(3):413-6. View

3.
TABAQCHALI S . The pathophysiological role of small intestinal bacterial flora. Scand J Gastroenterol Suppl. 1970; 6:139-63. View

4.
Varel V, Bryant M . Nutritional features of Bacteroides fragilis subsp. fragilis. Appl Microbiol. 1974; 28(2):251-7. PMC: 186696. DOI: 10.1128/am.28.2.251-257.1974. View

5.
Schjonsby H . The effect of bacteria on intestinal uptake of vitamin B 12 . I. Effect of cultures of blind-loop contents. Scand J Gastroenterol. 1972; 7(2):119-28. View