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Transplantation of Pluripotential Nuclei from Triploid Frog Tumors

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Journal Science
Specialty Science
Date 1969 Jul 25
PMID 5815255
Citations 36
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Abstract

Renal tumors were produced by injection of a cell fraction of a tumor into triploid tadpoles of Rana pipiens before they began feeding. Triploid tumor cells were dissociated and transplanted into activated and enucleated eggs. Pluripotency of the implanted nuclei was evidenced by the formation of swimming triploid tadpoles.

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