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Phenotypic Expressions of the Major Histocompatibility Locus in Man (HL-A): Leukocyte Antigens and Mixed Leukocyte Culture Reactivity

Overview
Journal J Exp Med
Date 1968 Oct 1
PMID 5675436
Citations 53
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Abstract

The evidence is reviewed that a single genetic system, the major histocompatibility locus in man, HL-A, determines most of the antigens measured by presently available leukocyte isoantisera, and also controls reactivity in one-way mixed leucocyte culture tests. Studies in 12 families are presented to support this conclusion. Some interesting exceptions to the general typing-MLC tests correlation are presented and discussed.

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