The Structure of the Chromatin Core Particle in Solution

Overview

Journal Nucleic Acids Res

Publisher Oxford University Press

Specialty Biochemistry

Date 1977 Sep 1

PMID 561952

Citations 31

Authors

J F Pardon

D L Worcester

J C Wooley

R I Cotter

D M Lilley

R M RICHARDS

Affiliations

Soon will be listed here.

Abstract

The shape and size of the nucleosomal core particle from chromatin has been examined by analysis of neutron and X-ray scattering data from dilute solutions. Calculations of scattering for many different models have been made and only one model was able to account for both the X-ray and neutron profiles. This model is an oblate structure with height about 50A and diameter 110A. The DNA is mainly confined to two annuli located at the top and bottom respectively of the core particle positioned on the outside of a compact protein core which has a height of about 40A and diameter about 73A.

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