» Articles » PMID: 5348431

Tremor Induced by Tetrabenazine

Overview
Journal Br J Pharmacol
Publisher Wiley
Specialty Pharmacology
Date 1969 Oct 1
PMID 5348431
Authors
Affiliations
Soon will be listed here.
Abstract

1. Acute administration of tetrabenazine produced tremor in cats, in doses which caused sedation but not hypothermia.2. The pattern of movements resembled shivering rather than Parkinsonism, and warming the skin suppressed the tremor.3. The tremor was not influenced by hyoscine.4. Tremor produced by amylobarbitone was essentially similar to that induced by tetrabenazine.

References
1.
POIRIER L, Sourkes T, Bouvier G, Boucher R, Carabin S . Striatal amines, experimental tremor and the effect of harmaline in the monkey. Brain. 1966; 89(1):37-52. DOI: 10.1093/brain/89.1.37. View

2.
Hornykiewicz O . Dopamine (3-hydroxytyramine) and brain function. Pharmacol Rev. 1966; 18(2):925-64. View

3.
Laverty R, SHARMAN D . MODIFICATION BY DRUGS OF THE METABOLISM OF 3,4-DIHYDROXYPHENYLETHYLAMINE, NORADRENALINE AND 5-HYDROXYTRYPTAMINE IN THE BRAIN. Br J Pharmacol Chemother. 1965; 24:759-72. PMC: 1704029. DOI: 10.1111/j.1476-5381.1965.tb01632.x. View

4.
Nikki P, TAMMISTO T . Halothane-induced heat loss and shivering in rats. Acta Anaesthesiol Scand. 1968; 12(3):125-34. DOI: 10.1111/j.1399-6576.1968.tb00418.x. View

5.
BRUMLIK J, MEANS E . Tremorine-tremor, shivering and acute cerebellar ataxia in the adult and child--a comparative study. Brain. 1969; 92(1):157-90. DOI: 10.1093/brain/92.1.157. View