Repair of Radiation-induced Damage to the Cell Division Mechanism of Escherichia Coli

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 1965 Jan 1

PMID 5327364

Citations 22

Authors

H I Adler

W D Fisher

A A Hardigree

G E STAPLETON

Affiliations

Soon will be listed here.

Abstract

Adler, Howard I. (Oak Ridge National Laboratory, Oak Ridge, Tenn.), William D. Fisher, Alice A. Hardigree, and George E. Stapleton. Repair of radiation-induced damage to the cell division mechanism of Escherichia coli. J. Bacteriol. 91:737-742. 1966.-Microscopic observations of irradiated populations of filamentous Escherichia coli cells indicated that filaments can be induced to divide by a substance donated by neighboring cells. We have made this observation the basis for a quantitative technique in which filaments are incubated in the presence of nongrowing donor cells. The presence of "donor" organisms promotes division and subsequent colony formation in filaments. "Donor" bacteria do not affect nonfilamentous cells. An extract of "donor" cells retains the division-promoting activity. The extract has been partially fractionated, and consists of a heat-stable and a heat-labile component. The heat-stable component is inactive in promoting cell division, but enhances the activity of the heat-labile component. The division-promoting system is discussed as a radiation repair mechanism and as a normal component of the cell division system in E. coli.

Citing Articles

The Genetic Basis for Mucoidy and Radiation Sensitivity in capR (lon) Mutants of E. coli K-12.

Bush J, Markovitz A Genetics. 1973; 74(2):215-25.

PMID: 17248613 PMC: 1212941. DOI: 10.1093/genetics/74.2.215.

Linkage map of Escherichia coli K-12, edition 10: the traditional map.

Berlyn M Microbiol Mol Biol Rev. 1998; 62(3):814-984.

PMID: 9729611 PMC: 98936. DOI: 10.1128/MMBR.62.3.814-984.1998.

Cytoplasmic membrane fraction that promotes septation in an Escherichia coli lon mutant.

Adler H, Carrasco A, Crow W, Gill J J Bacteriol. 1981; 147(2):326-32.

PMID: 7021526 PMC: 216049. DOI: 10.1128/jb.147.2.326-332.1981.

Influence of chromosome integrity on Escherichia coli cell division.

Markham B, Brubaker R J Bacteriol. 1980; 143(1):455-62.

PMID: 6995443 PMC: 294270. DOI: 10.1128/jb.143.1.455-462.1980.

Filamentous growth of Escherichia coli K12 elicited by dimeric, mixed-valence complexes of ruthenium.

Gibson J, Poole R, Hughes M, Rees J Arch Microbiol. 1984; 139(2-3):265-71.

PMID: 6393892 DOI: 10.1007/BF00402012.

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