Axonal Transport of Gangliosides in the Goldfish Optic Nerve

Overview

Journal Science

Specialty Science

Date 1972 Aug 18

PMID 5049309

Citations 16

Authors

D S Forman

R W Ledeen

Affiliations

Soon will be listed here.

Abstract

Radioactive glucosamine and N-acetylmannosamine injected into the goldfish eye are incorporated into gangliosides that undergo rapid axonal transport to the optic nerve terminals. All ganglioside fractions are labeled. These data provide the first evidence that axonal transport has a role in neuronal ganglioside function and metabolism.

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