» Articles » PMID: 495552

Folacin and Iron Status and Hematological Findings in Predominately Black Elderly Persons from Urban Low-income Households

Overview
Journal Am J Clin Nutr
Publisher Elsevier
Date 1979 Nov 1
PMID 495552
Citations 4
Authors
Affiliations
Soon will be listed here.
Abstract

The folacin and iron status and hemotological parameters of 193 persons 60 years of age and older from urban low-income households were evaluated. Of the serum folacin values 30% were between 3 and 6 ng/ml and 8% were below 3 ng/ml. Of these subjects 60% could be classified as "high risk" (less than 140 ng/ml) and 11% as "medium risk" (140 to 160 ng/ml) based on red blood cell folacin concentrations. Serum iron was normal (greater than 50 micrograms/dl) for all subjects as was transferrin saturation (greater than 15%). Hematological indices showed a 14% incidence of anemia (hemaglobin less than 12 g/dl), and 32% incidence of leukopenia (leukocytes less than 4.8 X 10(3)). These findings demonstrate widespread folacin deficiency and no evidence of iron deficiency in these elderly people.

Citing Articles

The causes and prevention of cancer: gaining perspective.

Ames B, Gold L Environ Health Perspect. 1997; 105 Suppl 4:865-73.

PMID: 9255573 PMC: 1470059. DOI: 10.1289/ehp.97105s4865.


Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage.

Blount B, Mack M, Wehr C, MacGregor J, Hiatt R, Wang G Proc Natl Acad Sci U S A. 1997; 94(7):3290-5.

PMID: 9096386 PMC: 20362. DOI: 10.1073/pnas.94.7.3290.


The causes and prevention of cancer.

Ames B, Gold L, Willett W Proc Natl Acad Sci U S A. 1995; 92(12):5258-65.

PMID: 7777494 PMC: 41674. DOI: 10.1073/pnas.92.12.5258.


Cytogenetic damage induced by folate deficiency in mice is enhanced by caffeine.

MacGregor J, Schlegel R, Wehr C, Alperin P, Ames B Proc Natl Acad Sci U S A. 1990; 87(24):9962-5.

PMID: 2263647 PMC: 55294. DOI: 10.1073/pnas.87.24.9962.