Inhibition of Collagen Synthesis by Alpha, Alpha1-dipyridyl in Human Skin Fibroblasts in Culture

Overview

Journal In Vitro

Specialties Anatomy & Histology
Cell Biology

Date 1973 Nov 1

PMID 4779003

Citations 4

Authors

B R Switzer

G K SUMMER

Affiliations

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References

Cooper G, Prockop D . Intracellular accumulation of protocollagen and extrusion of collagen by embryonic cartilage cells. J Cell Biol. 1968; 38(3):523-37. PMC: 2108381. DOI: 10.1083/jcb.38.3.523. View

Hutton Jr J, Trappel A, UDENFRIEND S . Requirements for alpha-ketoglutarate, ferrous ion and ascorbate by collagen proline hydroxylase. Biochem Biophys Res Commun. 1966; 24(2):179-84. DOI: 10.1016/0006-291x(66)90716-9. View

Margolis R, LUKENS L . The role of hydroxylation in the secretion of collagen by mouse fibroblasts in culture. Arch Biochem Biophys. 1971; 147(2):612-8. DOI: 10.1016/0003-9861(71)90419-x. View

Oyama V, Eagle H . Measurement of cell growth in tissue culture with a phenol reagent (folin-ciocalteau). Proc Soc Exp Biol Med. 1956; 91(2):305-7. DOI: 10.3181/00379727-91-22245. View

Switzer B, SUMMER G . Improved method for hydroxyproline analysis in tissue hydrolyzates. Anal Biochem. 1971; 39(2):487-91. DOI: 10.1016/0003-2697(71)90438-6. View

Switzer B, SUMMER G . Collagen synthesis in human skin fibroblasts: effects of ascorbate, -ketoglutarate and ferrous ion on proline hydroxylation. J Nutr. 1972; 102(6):721-8. DOI: 10.1093/jn/102.6.721. View

Bhatnagar R, Prockop D, Rosenbloom J . Intracellular pool of unhydroxylated polypeptide precursors of collagen. Science. 1967; 158(3800):492-4. DOI: 10.1126/science.158.3800.492. View

KLEINSMITH L, Allfrey V, Mirsky A . Phosphoprotein metabolism in isolated lymphocyte nuclei. Proc Natl Acad Sci U S A. 1966; 55(5):1182-9. PMC: 224297. DOI: 10.1073/pnas.55.5.1182. View

Peterkofsky B . Regulation of collagen secretion by ascorbic acid in 3T3 and chick embryo fibroblasts. Biochem Biophys Res Commun. 1972; 49(5):1343-50. DOI: 10.1016/0006-291x(72)90614-6. View

10.

GRIBBLE T, Comstock J, UDENFRIEND S . Collagen chain formation and peptidyl proline hydroxylation in monolayer tissue cultures of L-929 fibroblasts. Arch Biochem Biophys. 1969; 129(1):308-16. DOI: 10.1016/0003-9861(69)90180-5. View

11.

Smith B, Byers P, Martin G . Production of procollagen by human fibroblasts in culture. Proc Natl Acad Sci U S A. 1972; 69(11):3260-2. PMC: 389749. DOI: 10.1073/pnas.69.11.3260. View

12.

Bhatnagar R, Kivirikko K, Prockop D . Studies on the synthesis and intracellular accumulation of protocollagen in organ culture of embryonic cartilage. Biochim Biophys Acta. 1968; 154(1):196-207. DOI: 10.1016/0005-2795(68)90272-9. View

13.

Ramaley P, Rosenbloom J . Inhibition of proline and lysine hydroxylation prevents normal extrusion of collagen by 3T6 fibroblasts in culture. FEBS Lett. 1971; 15(1):59-64. DOI: 10.1016/0014-5793(71)80079-0. View

14.

JUVA K, Prockop D, Cooper G, LASH J . Hydroxylation of proline and the intracellular accumulation of a polypeptide precursor of collagen. Science. 1966; 152(3718):92-4. DOI: 10.1126/science.152.3718.92. View

15.

Patterson M, GREENE R . MEASUREMENT OF LOW ENERGY BETA-EMITTERS IN AQUEOUS SOLUTION BY LIQUID SCINTILLATION COUNTING OF EMULSIONS. Anal Chem. 1965; 37:854-7. DOI: 10.1021/ac60226a017. View

16.

DULBECCO R, Vogt M . Plaque formation and isolation of pure lines with poliomyelitis viruses. J Exp Med. 1954; 99(2):167-82. PMC: 2180341. DOI: 10.1084/jem.99.2.167. View

17.

Tsai R, Green H . Study of intracellular collagen precursors using DNA-cellulose chromatography. Nat New Biol. 1972; 237(75):171-3. DOI: 10.1038/newbio237171a0. View

18.

Peterkofsky B . The effect of ascorbic acid on collagen polypeptide synthesis and proline hydroxylation during the growth of cultured fibroblasts. Arch Biochem Biophys. 1972; 152(1):318-28. DOI: 10.1016/0003-9861(72)90221-4. View

19.

Peterkofsky B, UDENFRIEND S . CONVERSION OF PROLINE TO COLLAGEN HYDROXYPROLINE IN A CELL-FREE SYSTEM FROM CHICK EMBRYO. J Biol Chem. 1963; 238:3966-77. View