Some Aspects of the Modulation and Regulation of Collagen Synthesis in Vitro

Overview

Journal Mol Cell Biochem

Publisher Springer

Specialty Biochemistry

Date 1981 Jan 28

PMID 7015111

Citations 6

Authors

P K Muller

E KIRSCH

V Gauss-Muller

T Krieg

Affiliations

Soon will be listed here.

Abstract

We reviewed here a number of publications containing data on the quantitative aspects of collagen synthesis in vitro. In one section we discussed the factors which modulate the amount of collagen synthesized in various culture systems and in another section we presented experimental evidence for regulatory mechanisms operating in collagen synthesis on the transcriptional and/or translational levels. We believe that growing knowledge of the mechanisms controlling collagen synthesis will help us to understand and deal with fibrotic processes better.

Citing Articles

Low rate of procollagen conversion in dermatosparactic sheep fibroblasts is paralleled by increased synthesis of type I and type III collagens.

Wiestner M, Rohde H, HELLE O, Krieg T, Timpl R, Muller P EMBO J. 1982; 1(4):513-6.

PMID: 7188350 PMC: 553077. DOI: 10.1002/j.1460-2075.1982.tb01200.x.

Influence of cell density on collagen biosynthesis in fibroblast cultures.

Aumailley M, Krieg T, Razaka G, Muller P, BRICAUD H Biochem J. 1982; 206(3):505-10.

PMID: 7150259 PMC: 1158617. DOI: 10.1042/bj2060505.

Glucocorticoids stimulate collagen and noncollagen protein synthesis in cultured vascular smooth muscle cells.

Leitman D, Benson S, Johnson L J Cell Biol. 1984; 98(2):541-9.

PMID: 6693495 PMC: 2113086. DOI: 10.1083/jcb.98.2.541.

Collagen synthesis in generalized morphea.

Krieg T, Braun-Falco O, Perlish J, FLEISCHMAJER R Arch Dermatol Res. 1983; 275(6):393-6.

PMID: 6660911 DOI: 10.1007/BF00417340.

Synthetic activities of mass cultures and clones of human gingival fibroblasts.

Hassell T, PROVENZA D, Foster R Experientia. 1986; 42(1):66-9.

PMID: 3943601 DOI: 10.1007/BF01975899.

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