Gene Frequency Analysis of Chromosomal Initiation Sites in Bacillus Subtilis After Ultraviolet Light or X-ray Exposure

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 1972 Jan 1

PMID 4621630

Citations 3

Authors

D BILLEN

G Hellerman

L Carreira

Affiliations

Soon will be listed here.

Abstract

Bacillus subtilis was exposed to ultraviolet light (UV) or X rays, and gene frequency analysis was used to study the location of initiation sites of postirradiation deoxyribonucleic acid (DNA) synthesis. It was found that DNA synthesis resumes primarily from the origin after UV exposure. With X irradiation, the origin is not selectively replicated. Elevated origin-to-terminal marker ratios observed after UV exposure of exponentially growing cells were interpreted as evidence for selective UV resistance of the replicative origin region of the bacterial chromosome.

Citing Articles

Adaptive response of Bacillus subtilis to N-methyl-N'-nitro-N-nitrosoguanidine.

Hadden C, Foote R, Mitra S J Bacteriol. 1983; 153(2):756-62.

PMID: 6401705 PMC: 221694. DOI: 10.1128/jb.153.2.756-762.1983.

Genetic analysis of repair of ultraviolet damage by competent and noncompetent cells of Bacillus subtilis.

Hadden C, BILLEN D J Bacteriol. 1973; 113(1):88-95.

PMID: 4630515 PMC: 251606. DOI: 10.1128/jb.113.1.88-95.1973.

Postirradiation recovery dependent on the uvr-1 locus in Bacillus subtilis.

Hadden C J Bacteriol. 1976; 128(1):317-24.

PMID: 824273 PMC: 232858. DOI: 10.1128/jb.128.1.317-324.1976.

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