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Experimental Allergic Neuritis Induced by Sensitization with Galactocerebroside

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Journal Science
Specialty Science
Date 1979 Jun 8
PMID 451555
Citations 39
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Abstract

Thirteen of 31 rabbits immunized repeatedly with bovine brain galactocerebroside developed experimental allergic neuritis, manifested by flaccid paresis and hypesthesia of four limbs, 2 to 11 months after the initial inoculation. Electrophysiological studies revealed multifocal conduction block of peripheral nerves. Perivenular demyelinative lesions associated with phagocytic mononuclear cells occurred in spinal ganglia, roots, and less frequently in distal nerves.

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