Difference in Kinetic Properties Between Hexokinase Type I Isoenzymes from Various Rat Tissues with Reference to the Effect of a Thiol Inhibitor
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Hexokinase isoenzyme type I was purified from various rat tissues, and was subjected to kinetic studies in the presence or the absence of p-chloromercuribenzenesulphonate. The mode of the inhibition by the thiol inhibitor was different for the type I isoenzymes obtained from different tissues, suggesting that the type I isoenzymes from different tissues were not identical proteins.
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