Antibody-dependent and Spontaneous Lympholysis in Urologic Cancer Patients

Overview

Journal Br J Cancer

Specialty Oncology

Date 1979 Jun 1

PMID 444405

Citations 1

Authors

T L Ratliff

R E McCool

W J Catalona

Affiliations

Soon will be listed here.

Abstract

To evaluate cytotoxic function mediated by killer lymphocytes and macrophages in urological cancer patients, we examined antibody-dependent and spontaneous lympholysis of chicken erythrocyte target cells, which is mediated by macrophages. Our results demonstrate a discordance between cytotoxic mechanisms in cancer patients, killer-cell function being impaired whilst macrophage-mediated cytotoxicity was increased.

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