Pathways of Gluconeogenesis from L-serine in the Neonatal Rat
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Gluconeogenesis from amino acid precursors was increased in the perfused liver of neonatal rats compared with that of adults. Quinolinate (5mm) was less inhibitory to glucose formation from serine and hydroxyproline in the neonatal rat than in the adult, suggesting that the main route for glucose synthesis from these precursors in neonatal liver does not involve pyruvate as an intermediate.
Ichiyama A Proc Jpn Acad Ser B Phys Biol Sci. 2011; 87(5):274-86.
PMID: 21558762 PMC: 3165904. DOI: 10.2183/pjab.87.274.
Okuno E, Minatogawa Y, Nakamura M, Kamoda N, Nakanishi J, Makino M Biochem J. 1980; 189(3):581-90.
PMID: 6783036 PMC: 1162039. DOI: 10.1042/bj1890581.
Liver enzymes of serine metabolism during neonatal development of the rat.
Snell K Biochem J. 1980; 190(2):451-5.
PMID: 6781481 PMC: 1162111. DOI: 10.1042/bj1900451.
Snell K, Walker D Biochem J. 1974; 144(3):519-31.
PMID: 4377655 PMC: 1168530. DOI: 10.1042/bj1440519.
Snell K, Natsumeda Y, Weber G Biochem J. 1987; 245(2):609-12.
PMID: 3117048 PMC: 1148165. DOI: 10.1042/bj2450609.