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Cyclic Nucleotide-dependent Protein Kinases. IV. Widespread Occurrence of Adenosine 3',5'-monophosphate-dependent Protein Kinase in Various Tissues and Phyla of the Animal Kingdom

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Specialty Science
Date 1969 Dec 1
PMID 4393915
Citations 149
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Abstract

Adenosine 3',5'-monophosphate-dependent protein kinase activity was found in about thirty sources including many mammalian tissues as well as species representative of eight different invertebrate phyla. The data support a unifying theory for the mechanism of action of adenosine 3',5'-monophosphate, namely that its many and diverse effects are mediated through activation of tissue-specific protein kinases.

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