Acetylcholine Sensitivity and Distribution on Mouse Neuroblastoma Cells

Overview

Journal Science

Specialty Science

Date 1970 Feb 27

PMID 4312553

Citations 22

Authors

A J Harris

M J Dennis

Affiliations

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Abstract

Action potentials resulted from iontophoretic application of acetylcholine to cloned mouse neuroblastoma cells maintained in culture. Cell bodies were sensitive to acetylcholine, but half the cells were insensitive along one of their processes, suggesting an analogy with normal axons and dendrites. Some cells were electrically coupled via their processes, but no chemically mediated synaptic transmission was seen.

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