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Studies of Escherichia Coli in Gnotobiotic Pigs. I. Experimental Reproduction of Colibacillosis

Overview
Journal Can J Comp Med Vet Sci
Specialty Veterinary Medicine
Date 1966 Jul 1
PMID 4224293
Citations 15
Authors
E M Kohler
E H BOHL
Affiliations
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Abstract

The successful experimental production of colibacillosis in young gnotobiotic pigs by the oral administration of E. COLI (08:K.:H21 was accomplished. Colibacillosis was not produced in gnotobiotic pigs infected with either of the 2 other strains of E.COLI employed.Necropsy observations were presented and discussed. Emphasis was placed on the absence of grossly visible enteritis in pigs that died in the acute phase of the disease. The gross appearance of the intestinal tract changed some hours after death to resemble that associated with enteritis.Bacteremia was detected in the gnotobiotic pigs orally infected with each of the 3 strains of E. COLI, and the special characteristics of the colostrum-deprived pig were stressed as important factors in these findings.

Citing Articles

Polyserositis Induced by Escherichia coli in Gnotobiotic Swine.

Meyer R, Saxena S, RHOADES H Infect Immun. 1971; 3(1):41-4.

PMID: 16557944 PMC: 416104. DOI: 10.1128/iai.3.1.41-44.1971.

Experimental enteric colibacillosis in piglets.

Moon H, Sorensen D, SAUTTER J Can J Comp Med. 1968; 32(3):493-7.

PMID: 15846900 PMC: 1319283.

Pathogenesis of experimental salmonellosis: inhibition of protein synthesis by cytotoxin.

Koo F, Peterson J, Houston C, Molina N Infect Immun. 1984; 43(1):93-100.

PMID: 6360911 PMC: 263393. DOI: 10.1128/iai.43.1.93-100.1984.

The gnotobiotic animal as a tool in the study of host microbial relationships.

Gordon H, PESTI L Bacteriol Rev. 1971; 35(4):390-429.

PMID: 4945725 PMC: 378408. DOI: 10.1128/br.35.4.390-429.1971.

Response of gnotobiotic pigs to oral infection with an enteropathogenic and with an edema disease strain of Escherichia coli.

Miniats O Can Vet J. 1970; 11(3):52-6.

PMID: 4910034 PMC: 1695028.

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