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Checkmate Awaiting Strategy: Unlocking the Potential of Chimeric Antigen Receptor T-cell Therapy in Uveal Melanoma

Overview
Journal Front Oncol
Specialty Oncology
Date 2025 Mar 5
PMID 40040721
Authors
Affiliations
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References
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Ventin M, Cattaneo G, Arya S, Jia J, Gelmi M, Sun Y . Chimeric Antigen Receptor T Cell with an Inducible Caspase-9 Suicide Gene Eradicates Uveal Melanoma Liver Metastases via B7-H3 Targeting. Clin Cancer Res. 2024; 30(15):3243-3258. PMC: 11572477. DOI: 10.1158/1078-0432.CCR-24-0071. View

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Forsberg E, Lindberg M, Jespersen H, Alsen S, Olofsson Bagge R, Donia M . HER2 CAR-T Cells Eradicate Uveal Melanoma and T-cell Therapy-Resistant Human Melanoma in IL2 Transgenic NOD/SCID IL2 Receptor Knockout Mice. Cancer Res. 2019; 79(5):899-904. DOI: 10.1158/0008-5472.CAN-18-3158. View