Role of Skin-homing T-cells in Recurrent Episodes of Atopic Dermatitis: a Review

Overview

Journal Front Immunol

Specialty Allergy & Immunology

Date 2025 Mar 5

PMID 40040698

Authors

Huimin Guo

Huimin Yuan

Yanru Yu

Jingwei Sun

Yan Sun

Yang Tang

Fengjie Zheng

Affiliations

Soon will be listed here.

Abstract

Atopic dermatitis (AD) is a chronic relapsing disease with complex pathogenesis. Among them, inflammation is one of the primary pathogenesis of AD. AD is characterized by infiltration of lymphocytes into the skin's dermis, and the skin homing of lymphocytes plays an essential role in the recurrence of AD. Currently, there is more and more evidence to support this view. This article reviews the relevant role of T lymphocyte skin-homing-related molecules in the recurrence of AD to provide a reference for the cure of AD.

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