Narrative Review of Recent Developments and the Future of Penicillin Allergy De-labelling by Non-allergists

Overview

Journal NPJ Antimicrob Resist

Publisher Nature Portfolio

Date 2025 Jan 22

PMID 39843524

Authors

Neil Powell

Michael Blank

Akish Luintel

Shuayb Elkhalifa

Rashmeet Bhogal

Michael Wilcock

Michael Wakefield

Jonathan Sandoe

Affiliations

Soon will be listed here.

Abstract

This article outlines recent developments in non-allergist delivered penicillin allergy de-labelling (PADL), discusses remaining controversies and uncertainties and explores the future for non-allergist delivered PADL. Recent developments include national guidelines for non-allergist delivered PADL and validation of penicillin allergy risk assessment tools. Controversies remain on which penicillin allergy features are low risk of genuine allergy. In the future genetic or immunological tests may facilitate PADL.

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