» Articles » PMID: 39842428

SHIV Fights Back to Evade Destruction by ECD4-Ig but Not Without Suffering Debilitating Wounds

Overview
Journal Mol Ther
Publisher Cell Press
Date 2025 Jan 22
PMID 39842428
Authors
Affiliations
Soon will be listed here.
References
1.
Li Y, Migueles S, Welcher B, Svehla K, Phogat A, Louder M . Broad HIV-1 neutralization mediated by CD4-binding site antibodies. Nat Med. 2007; 13(9):1032-4. PMC: 2584972. DOI: 10.1038/nm1624. View

2.
Anastassopoulou C, Marozsan A, Matet A, Snyder A, Arts E, Kuhmann S . Escape of HIV-1 from a small molecule CCR5 inhibitor is not associated with a fitness loss. PLoS Pathog. 2007; 3(6):e79. PMC: 1885273. DOI: 10.1371/journal.ppat.0030079. View

3.
OHagan D, Shandilya S, Hopkins L, Hahn P, Fuchs S, Martinez-Navio J . In vivo evolution of env in SHIV-AD8-infected rhesus macaques after AAV-vectored delivery of eCD4-Ig. Mol Ther. 2024; 33(2):560-579. PMC: 11853013. DOI: 10.1016/j.ymthe.2024.12.015. View

4.
Ratcliff A, Shi W, Arts E . HIV-1 resistance to maraviroc conferred by a CD4 binding site mutation in the envelope glycoprotein gp120. J Virol. 2012; 87(2):923-34. PMC: 3554087. DOI: 10.1128/JVI.01863-12. View

5.
Fetzer I, Gardner M, Davis-Gardner M, Prasad N, Alfant B, Weber J . eCD4-Ig Variants That More Potently Neutralize HIV-1. J Virol. 2018; 92(12). PMC: 5974481. DOI: 10.1128/JVI.02011-17. View