Cerebrovascular Disease in Dementia: the Importance of Atrial Fibrillation

Overview

Journal Postgrad Med J

Publisher Oxford University Press

Date 1985 Mar 1

PMID 3983054

Citations 8

Authors

P J Ratcliffe

G K Wilcock

Affiliations

Soon will be listed here.

Abstract

The relationship between cardiovascular disease and cerebral infarction was analysed in a prospectively assessed post mortem series of 48 demented patients. Hypertension was rare in this group of patients whose mean age was 82.7 y. Atrial fibrillation was the most important underlying cardiac abnormality. It is suggested that atrial fibrillation is more important than hypertension in the aetiology of cerebral infarction in the very aged and that this may be relevant to the pathogenesis of cerebrovascular dementia.

Citing Articles

Association between Atrial Fibrillation and Risk of Alzheimer's Disease and Vascular Dementia: A Systematic Review and Meta-analysis.

Zheng Y, Li G Ann Indian Acad Neurol. 2024; 27(6):619-628.

PMID: 39652360 PMC: 11745263. DOI: 10.4103/aian.aian_62_24.

Ablation of atrial fibrillation and dementia risk reduction during long-term follow-up: a nationwide population-based study.

Li G, Chen Y, Lin Y, Chien K, Hsieh Y, Chung F Europace. 2023; 25(5).

PMID: 37097046 PMC: 10228604. DOI: 10.1093/europace/euad109.

Concurrent cardiac transthyretin and brain β amyloid accumulation among the older adults: The Hisayama study.

Hamasaki H, Shijo M, Nakamura A, Honda H, Yamada Y, Oda Y Brain Pathol. 2021; 32(1):e13014.

PMID: 34390072 PMC: 8713523. DOI: 10.1111/bpa.13014.

Atrial Fibrillation and Risk of Dementia: Epidemiology, Mechanisms, and Effect of Anticoagulation.

da Silva R, Miranda C, Liu T, Tse G, Roever L Front Neurosci. 2019; 13:18.

PMID: 30766470 PMC: 6365433. DOI: 10.3389/fnins.2019.00018.

Heart disease as a risk factor for dementia.

Justin B, Turek M, Hakim A Clin Epidemiol. 2013; 5:135-45.

PMID: 23658499 PMC: 3641811. DOI: 10.2147/CLEP.S30621.

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