» Articles » PMID: 39771504

Innovative Approaches to Enhancing the Biomedical Properties of Liposomes

Overview
Journal Pharmaceutics
Publisher MDPI
Date 2025 Jan 8
PMID 39771504
Authors
Affiliations
Soon will be listed here.
Abstract

Liposomes represent a promising class of drug delivery systems that enhance the therapeutic efficacy and safety of various pharmaceutical agents. Also, they offer numerous advantages compared to traditional drug delivery methods, including targeted delivery to specific sites, controlled release, and fewer side effects. This review meticulously examines the methodologies employed in the preparation and characterization of liposomal formulations. With the rising incidence of adverse drug reactions, there is a pressing need for innovative delivery strategies that prioritize selectivity, specificity, and safety. Nanomedicine promises to revolutionize diagnostics and treatments, addressing current limitations and improving disease management, including cancer, which remains a major global health challenge. This paper aims to conduct a comprehensive study on the interest of biomedical research regarding nanotechnology and its implications for further applications.

References
1.
Silli E, Li M, Shao Y, Zhang Y, Hou G, Du J . Liposomal nanostructures for Gemcitabine and Paclitaxel delivery in pancreatic cancer. Eur J Pharm Biopharm. 2023; 192:13-24. DOI: 10.1016/j.ejpb.2023.09.014. View

2.
Xia H, Li F, Hu X, Park W, Wang S, Jang Y . pH-Sensitive Pt Nanocluster Assembly Overcomes Cisplatin Resistance and Heterogeneous Stemness of Hepatocellular Carcinoma. ACS Cent Sci. 2016; 2(11):802-811. PMC: 5126722. DOI: 10.1021/acscentsci.6b00197. View

3.
Lian T, Ho R . Trends and developments in liposome drug delivery systems. J Pharm Sci. 2001; 90(6):667-80. DOI: 10.1002/jps.1023. View

4.
Ong S, Chitneni M, Lee K, Ming L, Yuen K . Evaluation of Extrusion Technique for Nanosizing Liposomes. Pharmaceutics. 2016; 8(4). PMC: 5198018. DOI: 10.3390/pharmaceutics8040036. View

5.
Xu X, Wang L, Xu H, Huang X, Qian Y, Xiang J . Clinical comparison between paclitaxel liposome (Lipusu®) and paclitaxel for treatment of patients with metastatic gastric cancer. Asian Pac J Cancer Prev. 2013; 14(4):2591-4. DOI: 10.7314/apjcp.2013.14.4.2591. View