Comparison of Short-Term Clinical Outcomes After Implantation of Two Monofocal, Aspheric Intraocular Lenses

Overview

Journal Diagnostics (Basel)

Specialty Radiology

Date 2025 Jan 8

PMID 39767223

Authors

Jeewon Han

Yea Eun Lee

Nahyun Park

Chung Min Lee

Yoo Young Jeon

Hayoung Lee

Kyu Sang Eah

Yeji Yoon

Ho Seok Chung

Jae Yong Kim

Jiwon Jeong

Hun Lee

Affiliations

Soon will be listed here.

Abstract

Objectives: This study compared the visual outcomes and optical quality of two monofocal, aspheric intraocular lenses (IOLs; CT LUCIA 621P, Carl Zeiss Meditec; Eyhance ICB00, Johnson & Johnson Vision) by evaluating visual acuity, contrast sensitivity, and higher-order aberrations 1 month post-cataract surgery.

Methods: In this retrospective, comparative study, 120 eyes (72 patients) that underwent cataract surgery with either CT LUCIA 621P (Lucia group) or Eyhance ICB00 (Eyhance group) implantation (60 eyes/group) were retrospectively investigated. Visual acuity at various distances and defocus curves were measured 1 month postoperatively. Optical quality was assessed by comparing contrast sensitivity and internal coma, spherical, and total aberrations by using iTrace (Tracey Technology), a ray-tracing-type aberrometer.

Results: The visual acuity and defocus curves were similar between the two IOLs 1 month postoperatively. The Lucia group showed better contrast sensitivity at higher spatial frequencies: 12 cpd ( < 0.001, 1.32 LogCS vs. 1.02 LogCS) and 18 cpd ( = 0.009, 0.74 LogCS vs. 0.47 LogCS) unilaterally and 18 cpd ( = 0.044, 0.94 LogCS vs. 0.60 LogCS) bilaterally. Postoperative internal spherical aberration was significantly lower in the Lucia group ( < 0.001, -0.04 µm vs. -0.003 µm). Internal coma and total aberrations were similar.

Conclusions: The visual acuity and defocus curves of the Lucia and Eyhance groups were comparable 1 month post-cataract surgery. The Lucia group's superior contrast sensitivity and lower postoperative internal spherical aberration were due to differences in IOL designs, particularly the power variation patterns.

References

Hernandez-Martinez A, Diaz-Del-Rio M, Ruiz-Santos M, Ruiz-Mesa R, Tana-Rivero P . Refractive and Visual Outcomes of a Monofocal Non-Constant Aberration Aspheric Intraocular Lens. Clin Ophthalmol. 2022; 16:2521-2530. PMC: 9376001. DOI: 10.2147/OPTH.S373587. View

Vega F, Millan M, Gil M, Garzon N . Optical Performance of a Monofocal Intraocular Lens Designed to Extend Depth of Focus. J Refract Surg. 2020; 36(9):625-632. DOI: 10.3928/1081597X-20200710-01. View

Steinmuller L, Greve D, Rua Amaro D, Bertelmann E, von Sonnleithner C . Analysis of higher-order aberrations in relation to the clinical outcome of an enhanced monofocal IOL. Eur J Ophthalmol. 2022; 33(6):2096-2105. PMC: 10590024. DOI: 10.1177/11206721221134171. View

Unsal U, Sabur H . Comparison of new monofocal innovative and standard monofocal intraocular lens after phacoemulsification. Int Ophthalmol. 2020; 41(1):273-282. DOI: 10.1007/s10792-020-01579-y. View

Auffarth G, Gerl M, Tsai L, Janakiraman D, Jackson B, Alarcon A . Clinical evaluation of a new monofocal IOL with enhanced intermediate function in patients with cataract. J Cataract Refract Surg. 2020; 47(2):184-191. DOI: 10.1097/j.jcrs.0000000000000399. View

Morales E, Rocha K, Chalita M, Nose W, Avila M . Comparison of optical aberrations and contrast sensitivity between aspheric and spherical intraocular lenses. J Refract Surg. 2011; 27(10):723-8. DOI: 10.3928/1081597X-20110708-02. View

Alarcon A, Canovas C, Koopman B, Weeber H, Auffarth G, Piers P . Enhancing the Intermediate Vision of Monofocal Intraocular Lenses Using a Higher Order Aspheric Optic. J Refract Surg. 2020; 36(8):520-527. DOI: 10.3928/1081597X-20200612-01. View

Tognetto D, Cecchini P, Giglio R, Turco G . Surface profiles of new-generation IOLs with improved intermediate vision. J Cataract Refract Surg. 2020; 46(6):902-906. DOI: 10.1097/j.jcrs.0000000000000215. View

Corbelli E, Iuliano L, Bandello F, Fasce F . Comparative analysis of visual outcome with 3 intraocular lenses: monofocal, enhanced monofocal, and extended depth of focus. J Cataract Refract Surg. 2021; 48(1):67-74. DOI: 10.1097/j.jcrs.0000000000000706. View

10.

Borkenstein A, Borkenstein E . Long-term clinical results and scanning electron microscopic analysis of the aspheric, hydrophobic, acrylic intraocular lens CT LUCIA 611P(Y). Clin Ophthalmol. 2018; 12:1219-1227. PMC: 6038869. DOI: 10.2147/OPTH.S167895. View

11.

Goslings O, Veraart H, van de Laar-Muskens J, Pinero D . Clinical outcomes with an aspheric monofocal and a new enhanced monofocal intraocular lens with modified optical profile. Graefes Arch Clin Exp Ophthalmol. 2023; 261(8):2315-2326. PMC: 10368552. DOI: 10.1007/s00417-023-06128-8. View

12.

Deshpande R, Satijia A, Dole K, Mangiraj V, Deshpande M . Effects on ocular aberration and contrast sensitivity after implantation of spherical and aspherical monofocal intraocular lens - A comparative study. Indian J Ophthalmol. 2022; 70(8):2862-2865. PMC: 9672777. DOI: 10.4103/ijo.IJO_19_22. View

13.

Garcia-Tomas B, Marin-Sanchez J, Garcia-Elskamp C, Alcon-Ruiz E, Montesinos-Lopez L, Garcia Martinez-Lozano B . Clinical Outcomes of a Monofocal, Optimized, Aspheric, Hydrophobic Acrylic Intraocular Lens Implant. Clin Ophthalmol. 2023; 17:3215-3224. PMC: 10617528. DOI: 10.2147/OPTH.S434378. View

14.

Kang K, Song M, Kim K, Hwang K, Kwon Y, Koh K . Visual Performance and Optical Quality after Implantation of a New Generation Monofocal Intraocular Lens. Korean J Ophthalmol. 2021; 35(2):112-119. PMC: 8046615. DOI: 10.3341/kjo.2020.1115. View

15.

Miret J, Camps V, Garcia C, Caballero M, Gonzalez-Leal J . Analysis and comparison of monofocal, extended depth of focus and trifocal intraocular lens profiles. Sci Rep. 2022; 12(1):8654. PMC: 9126942. DOI: 10.1038/s41598-022-12694-4. View

16.

Gigon E, Bouthour W, Panos G, Pajic B, Massa H . Real world outcomes of the new Tecnis Eyhance IOL. Eur J Ophthalmol. 2022; 33(3):1390-1397. PMC: 10152560. DOI: 10.1177/11206721221146675. View

17.

Micheletti J, McCauley M, Duncan N, Hall B . Biometric Indicators for Maximizing Intermediate Vision with a Monofocal IOL. Clin Ophthalmol. 2023; 17:3739-3746. PMC: 10712349. DOI: 10.2147/OPTH.S441172. View

18.

Nanavaty M, Ashena Z, Gallagher S, Borkum S, Frattaroli P, Barbon E . Visual Acuity, Wavefront Aberrations, and Defocus Curves With an Enhanced Monofocal and a Monofocal Intraocular Lens: A Prospective, Randomized Study. J Refract Surg. 2022; 38(1):10-20. DOI: 10.3928/1081597X-20211109-02. View

19.

Lopes D, Loureiro T, Carreira R, Rodrigues Barros S, Cardoso J, Campos P . Comparative evaluation of visual outcomes after bilateral implantation of an advanced or conventional monofocal intraocular lens. Eur J Ophthalmol. 2021; 32(1):229-234. DOI: 10.1177/1120672121995343. View

20.

Wan K, Au A, Kua W, Ng A, Cheng G, Lam N . Enhanced Monofocal Versus Conventional Monofocal Intraocular Lens in Cataract Surgery: A Meta-analysis. J Refract Surg. 2022; 38(8):538-546. DOI: 10.3928/1081597X-20220707-01. View