HOTTIP Rs1859168 C > A Polymorphism Reduces Neuroblastoma Susceptibility in Chinese Children

Overview

Journal Eur J Pediatr

Specialty Pediatrics

Date 2024 Dec 24

PMID 39718648

Authors

Ting Zhang

Huimin Yin

Jiejie Guo

Jiaming Chang

Mengjia Li

Jing He

Chunlei Zhou

Affiliations

Soon will be listed here.

Abstract

Conclusion: We found that HOTTIP gene polymorphisms were associated with a reduced likelihood of neuroblastoma in Chinese children. Further studies with large cohorts and diverse ethnicities are warranted to verify our results.

What Is Known: • Genetic variations can influence neuroblastoma susceptibility. HOTTIP gene polymorphisms may alter an individual's susceptibility to various cancers.

What Is New: • HOTTIP gene polymorphisms were associated with a reduced risk of neuroblastoma in Chinese children.

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