Advancing Digital Sensing in Mental Health Research

Overview

Journal NPJ Digit Med

Specialty Medical Informatics

Date 2024 Dec 18

PMID 39695319

Authors

Samir Akre

Darsol Seok

Christopher Douglas

Adrian Aguilera

Simona Carini

Jessilyn Dunn

Matthew Hotopf

David C Mohr

Alex A T Bui

Nelson B Freimer

Affiliations

Soon will be listed here.

Abstract

Digital sensing tools, like smartphones and wearables, offer transformative potential for mental health research by enabling scalable, longitudinal data collection. Realizing this promise requires overcoming significant challenges including limited data standards, underpowered studies, and a disconnect between research aims and community needs. This report, based on the 2023 Workshop on Advancing Digital Sensing Tools for Mental Health, articulates strategies to address these challenges to ensure rigorous, equitable, and impactful research.

References

Estrin D, Sim I . Health care delivery. Open mHealth architecture: an engine for health care innovation. Science. 2010; 330(6005):759-60. DOI: 10.1126/science.1196187. View

Manta C, Mahadevan N, Bakker J, Ozen Irmak S, Izmailova E, Park S . EVIDENCE Publication Checklist for Studies Evaluating Connected Sensor Technologies: Explanation and Elaboration. Digit Biomark. 2021; 5(2):127-147. PMC: 8215946. DOI: 10.1159/000515835. View

Johnson A, Bulgarelli L, Shen L, Gayles A, Shammout A, Horng S . MIMIC-IV, a freely accessible electronic health record dataset. Sci Data. 2023; 10(1):1. PMC: 9810617. DOI: 10.1038/s41597-022-01899-x. View

Pratap A, Chaibub Neto E, Snyder P, Stepnowsky C, Elhadad N, Grant D . Indicators of retention in remote digital health studies: a cross-study evaluation of 100,000 participants. NPJ Digit Med. 2020; 3:21. PMC: 7026051. DOI: 10.1038/s41746-020-0224-8. View

Gupta R, Iyengar R, Sharma M, Cannuscio C, Merchant R, Asch D . Consumer Views on Privacy Protections and Sharing of Personal Digital Health Information. JAMA Netw Open. 2023; 6(3):e231305. PMC: 9982693. DOI: 10.1001/jamanetworkopen.2023.1305. View

Moher D, Hopewell S, Schulz K, Montori V, Gotzsche P, Devereaux P . CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. BMJ. 2010; 340:c869. PMC: 2844943. DOI: 10.1136/bmj.c869. View

Chikwetu L, Miao Y, Woldetensae M, Bell D, Goldenholz D, Dunn J . Does deidentification of data from wearable devices give us a false sense of security? A systematic review. Lancet Digit Health. 2023; 5(4):e239-e247. PMC: 10040444. DOI: 10.1016/S2589-7500(22)00234-5. View

Bent B, Wang K, Grzesiak E, Jiang C, Qi Y, Jiang Y . The digital biomarker discovery pipeline: An open-source software platform for the development of digital biomarkers using mHealth and wearables data. J Clin Transl Sci. 2021; 5(1):e19. PMC: 8057397. DOI: 10.1017/cts.2020.511. View

Sullivan P . The psychiatric GWAS consortium: big science comes to psychiatry. Neuron. 2010; 68(2):182-6. PMC: 2991765. DOI: 10.1016/j.neuron.2010.10.003. View

10.

Kiang M, Chen J, Krieger N, Buckee C, Alexander M, Baker J . Sociodemographic characteristics of missing data in digital phenotyping. Sci Rep. 2021; 11(1):15408. PMC: 8322366. DOI: 10.1038/s41598-021-94516-7. View

11.

Richardson S, Lawrence K, Schoenthaler A, Mann D . A framework for digital health equity. NPJ Digit Med. 2022; 5(1):119. PMC: 9387425. DOI: 10.1038/s41746-022-00663-0. View

12.

Parnell L, Lindenbaum P, Shameer K, DallOlio G, Swan D, Jensen L . BioStar: an online question & answer resource for the bioinformatics community. PLoS Comput Biol. 2011; 7(10):e1002216. PMC: 3203049. DOI: 10.1371/journal.pcbi.1002216. View

13.

Schulz K, Altman D, Moher D . CONSORT 2010 statement: Updated guidelines for reporting parallel group randomised trials. J Pharmacol Pharmacother. 2011; 1(2):100-7. PMC: 3043330. DOI: 10.4103/0976-500X.72352. View

14.

Fried E . Moving forward: how depression heterogeneity hinders progress in treatment and research. Expert Rev Neurother. 2017; 17(5):423-425. DOI: 10.1080/14737175.2017.1307737. View

15.

de Angel V, Lewis S, White K, Oetzmann C, Leightley D, Oprea E . Digital health tools for the passive monitoring of depression: a systematic review of methods. NPJ Digit Med. 2022; 5(1):3. PMC: 8752685. DOI: 10.1038/s41746-021-00548-8. View

16.

Shandhi M, Singh K, Janson N, Ashar P, Singh G, Lu B . Assessment of ownership of smart devices and the acceptability of digital health data sharing. NPJ Digit Med. 2024; 7(1):44. PMC: 10883993. DOI: 10.1038/s41746-024-01030-x. View

17.

Mailman M, Feolo M, Jin Y, Kimura M, Tryka K, Bagoutdinov R . The NCBI dbGaP database of genotypes and phenotypes. Nat Genet. 2007; 39(10):1181-6. PMC: 2031016. DOI: 10.1038/ng1007-1181. View

18.

Kainec K, Caccavaro J, Barnes M, Hoff C, Berlin A, Spencer R . Evaluating Accuracy in Five Commercial Sleep-Tracking Devices Compared to Research-Grade Actigraphy and Polysomnography. Sensors (Basel). 2024; 24(2). PMC: 10820351. DOI: 10.3390/s24020635. View

19.

Wardenaar K, de Jonge P . Diagnostic heterogeneity in psychiatry: towards an empirical solution. BMC Med. 2013; 11:201. PMC: 3846412. DOI: 10.1186/1741-7015-11-201. View

20.

Abdellaoui A, Yengo L, Verweij K, Visscher P . 15 years of GWAS discovery: Realizing the promise. Am J Hum Genet. 2023; 110(2):179-194. PMC: 9943775. DOI: 10.1016/j.ajhg.2022.12.011. View