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Malaria Pervasiveness in Sub-Saharan Africa: Overcoming the Scuffle

Overview
Specialty General Medicine
Date 2024 Dec 10
PMID 39654176
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Abstract

Malaria has posed a momentous health and economic burden to the Sub-Saharan African region. The Sub-Saharan African region accounts for more than 90% of global malaria-related mortality and morbidity. Pregnant women and children under 5 years old are the most vulnerable. Mosquitoes transmit the plasmodium which is the parasite responsible for malaria. The climatic conditions, poverty, and poor healthcare system of the Sub-Saharan African region are some factors fueling this menace. There have been concerted efforts to annihilate malaria but the scuffle has been a tedious one. Malarial eradication campaigns have been focused on mosquito control through the use of insecticide-treated bed nets, use of indoor insecticide sprays, and use of larvicides. The use of artemisinin in combination with other drugs has been effective to some extent. Despite the aforementioned strategies, the pervasiveness of malaria infection in the Sub-Saharan African region is worrisome. Thus, strengthening the already existing control measures, finding novel measures through intensive research, and embracing malaria vaccination could help accelerate the overcoming of this scuffle. In this review, we utilized relevant published data from various databases to reexamine the factors fueling malaria pervasiveness in this region and spelled out point-by-point intervention protocols to end malaria scuffle.

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References
1.
De Beaudrap P, Nabasumba C, Grandesso F, Turyakira E, Schramm B, Boum 2nd Y . Heterogeneous decrease in malaria prevalence in children over a six-year period in south-western Uganda. Malar J. 2011; 10:132. PMC: 3120731. DOI: 10.1186/1475-2875-10-132. View

2.
Antony H, Parija S . Antimalarial drug resistance: An overview. Trop Parasitol. 2016; 6(1):30-41. PMC: 4778180. DOI: 10.4103/2229-5070.175081. View

3.
Egwu C, Aloke C, Chukwu J, Agwu A, Alum E, Tsamesidis I . A world free of malaria: It is time for Africa to actively champion and take leadership of elimination and eradication strategies. Afr Health Sci. 2023; 22(4):627-640. PMC: 10117514. DOI: 10.4314/ahs.v22i4.68. View

4.
Chilot D, Mondelaers A, Alem A, Asres M, Yimer M, Toni A . Pooled prevalence and risk factors of malaria among children aged 6-59 months in 13 sub-Saharan African countries: A multilevel analysis using recent malaria indicator surveys. PLoS One. 2023; 18(5):e0285265. PMC: 10231787. DOI: 10.1371/journal.pone.0285265. View

5.
Tsegaye A, Ayele A, Birhanu S . Prevalence and associated factors of malaria in children under the age of five years in Wogera district, northwest Ethiopia: A cross-sectional study. PLoS One. 2021; 16(10):e0257944. PMC: 8504743. DOI: 10.1371/journal.pone.0257944. View