Viruses in the Female Lower Reproductive Tract: a Systematic Descriptive Review of Metagenomic Investigations

Overview

Journal NPJ Biofilms Microbiomes

Date 2024 Nov 25

PMID 39587088

Authors

Layla Honorato

Heuder Gustavo Oliveira Paiao

Antonio Charlys da Costa

Tania Regina Tozetto-Mendoza

Maria Cassia Mendes-Correa

Steven S Witkin

Affiliations

Soon will be listed here.

Abstract

The lower female reproductive tract (FRT) hosts a complex microbial environment, including eukaryotic and prokaryotic viruses (the virome), whose roles in health and disease are not fully understood. This review consolidates findings on FRT virome composition, revealing the presence of various viral families and noting significant gaps in knowledge. Understanding interactions between the virome, microbiome, and immune system will provide novel insights for preventing and managing lower genital tract disorders.

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