Tuberous Sclerosis: a Clinicoradiological Evaluation of 110 Cases with Particular Reference to Atypical Presentation

Overview

Journal Neuroradiology

Specialties Neurology
Radiology

Date 1986 Jan 1

PMID 3951687

Citations 29

Authors

D P KINGSLEY

B E Kendall

C R Fitz

Affiliations

Soon will be listed here.

Abstract

CT scans on 110 children with a diagnosis of tuberous sclerosis have been compared with the clinical features of the disease. Patients with definite radiological as well as definite or suggestive clinical features accounted for only 80% of cases. 16% had positive radiological and negative clinical features and 4% had positive clinical and negative radiological features. There is little relationship between the mental development and the incidence of periventricular tubers or cortical and white matter lesions. In 15 patients older than 7 years the diagnosis was only made at the time of CT. Cerebral atrophy was not a prominent feature. Giant cell astrocytomas were present in 14%, one third of whom presented for the first time.

Citing Articles

Atypical case of tuberous sclerosis with isolated neurologic findings: A case report.

Devkota S, Bhatta O, Kalikote A, Gyawali P, Lamichhane S Clin Case Rep. 2024; 12(9):e9379.

PMID: 39229295 PMC: 11369680. DOI: 10.1002/ccr3.9379.

Brachial artery aneurysm and bilateral posterior circulation strokes in a young child with tuberous sclerosis complex.

Meyer J, Graydon A, Muthukumaraswamy C, Jones H BMJ Case Rep. 2023; 16(11).

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All tubers are not created equal: Cerebellar tubers in a pediatric patient with tuberous sclerosis.

Weerasinghe S, Sato T Radiol Case Rep. 2020; 16(3):497-499.

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Dysplasia and overgrowth: magnetic resonance imaging of pediatric brain abnormalities secondary to alterations in the mechanistic target of rapamycin pathway.

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