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All Tubers Are Not Created Equal: Cerebellar Tubers in a Pediatric Patient with Tuberous Sclerosis

Overview
Journal Radiol Case Rep
Publisher Elsevier
Specialty Radiology
Date 2020 Dec 28
PMID 33363690
Citations 1
Authors
Sanjeeva Weerasinghe
Takashi S Sato
Affiliations
Soon will be listed here.
Abstract

Tuberous sclerosis complex (TSC) is a rare autosomal dominant disease characterized by multiple tumors throughout the body. Supratentorial hamartomas (or tubers), are a very common CNS feature of TSC. Cerebellar tubers are much less common in TSC. We present an interesting case of cerebellar tuber in a 14-year-old patient with TSC, highlighting clinical and diagnostic criteria for TSC and review the unique features of cerebellar tubers, differentiating these lesions from their more common supratentorial counterparts. This case serves as an educational tool to improve awareness of cerebellar tubers in patients with tuberous sclerosis.

Citing Articles

Incidence and Characteristics of Cerebellar Atrophy/Volume Loss in Children with Confirmed Diagnosis of Tuberous Sclerosis Complex.

Mertiri L, Boltshauser E, Kralik S, Desai N, Lequin M, Huisman T Children (Basel). 2024; 11(6).

PMID: 38929207 PMC: 11201845. DOI: 10.3390/children11060627.

References
1.
Kingswood J, dAugeres G, Belousova E, Ferreira J, Carter T, Castellana R . TuberOus SClerosis registry to increase disease Awareness (TOSCA) - baseline data on 2093 patients. Orphanet J Rare Dis. 2017; 12(1):2. PMC: 5217262. DOI: 10.1186/s13023-016-0553-5. View
2.
Kalantari B, Salamon N . Neuroimaging of tuberous sclerosis: spectrum of pathologic findings and frontiers in imaging. AJR Am J Roentgenol. 2008; 190(5):W304-9. DOI: 10.2214/AJR.07.2928. View
3.
Altman N, Purser R, Post M . Tuberous sclerosis: characteristics at CT and MR imaging. Radiology. 1988; 167(2):527-32. DOI: 10.1148/radiology.167.2.3357966. View
4.
Baskin Jr H . The pathogenesis and imaging of the tuberous sclerosis complex. Pediatr Radiol. 2008; 38(9):936-52. DOI: 10.1007/s00247-008-0832-y. View
5.
Ertan G, Arulrajah S, Tekes A, Jordan L, Huisman T . Cerebellar abnormality in children and young adults with tuberous sclerosis complex: MR and diffusion weighted imaging findings. J Neuroradiol. 2010; 37(4):231-8. DOI: 10.1016/j.neurad.2009.12.006. View