Impact of Probiotics-derived Extracellular Vesicles on Livestock Gut Barrier Function

Overview

Journal J Anim Sci Biotechnol

Publisher Biomed Central

Date 2024 Nov 7

PMID 39506860

Authors

Yuhan Zhang

Mengzhen Song

Jinping Fan

Xuming Guo

Shiyu Tao

Affiliations

Soon will be listed here.

Abstract

Probiotic extracellular vesicles (pEVs) are biologically active nanoparticle structures that can regulate the intestinal tract through direct or indirect mechanisms. They enhance the intestinal barrier function in livestock and poultry and help alleviate intestinal diseases. The specific effects of pEVs depend on their internal functional components, including nucleic acids, proteins, lipids, and other substances. This paper presents a narrative review of the impact of pEVs on the intestinal barrier across various segments of the intestinal tract, exploring their mechanisms of action while highlighting the limitations of current research. Investigating the mechanisms through which probiotics operate via pEVs could deepen our understanding and provide a theoretical foundation for their application in livestock production.

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