Long-term Effects of Non-pharmacological Interventions in Adolescents and Young Adults with Type 1 Diabetes: A Systematic Review and Meta-analysis

Overview

Journal Worldviews Evid Based Nurs

Specialty Nursing

Date 2024 Nov 5

PMID 39497508

Authors

DaeEun Lee

Haejung Lee

Misoon Lee

Gaeun Park

Affiliations

Soon will be listed here.

Abstract

Background: Consistent diabetes control is crucial for patients with type 1 diabetes (T1D) to prevent diabetic complications. Analyzing the long-term effects of non-pharmacological interventions can improve diabetes management.

Aim: To examine the long-term effects of non-pharmacological interventions in adolescents and young adults with T1D through a systematic review and meta-analysis of randomized controlled trials (RCTs).

Methods: The searches, without any year limitations, were conducted in seven databases. Two reviewers independently performed data extraction and risk of bias assessments. The meta-analysis was conducted using the RevMan 5.4 program and R Studio. The study was registered with PROSPERO (CRD42024503185).

Results: A total of 40 studies were included in the systematic review, of which 28 were included in the meta-analysis. Notably, non-pharmacological interventions were effective in improving glycated hemoglobin (HbA1c) at 6 months and self-care at >12 months of follow-up. Subgroup analyses revealed that combined interventions encompassing self-care behavior management, education, and psychological interventions could enhance self-care. Additionally, a combination of face-to-face and telephonic communication was effective in improving HbA1c.

Linking Evidence To Action: Non-pharmacological interventions are effective in improving HbA1c levels and self-care in adolescents and young adults undergoing long-term treatment. However, few studies have analyzed their effects on cardiovascular disease risk factors. Future studies should investigate the long-term effects of non-pharmacological interventions.

Citing Articles

Long-term effects of non-pharmacological interventions in adolescents and young adults with type 1 diabetes: A systematic review and meta-analysis.

Lee D, Lee H, Lee M, Park G Worldviews Evid Based Nurs. 2024; 21(6):665-677.

PMID: 39497508 PMC: 11655730. DOI: 10.1111/wvn.12751.

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