Surfactin from Enhances Immune Response and Contributes to the Maintenance of Intestinal Microbial Homeostasis

Overview

Journal Microbiol Spectr

Specialty Microbiology

Date 2024 Oct 29

PMID 39470280

Authors

Junpeng Jia

Mei Fu

Wenxin Ji

Ningna Xiong

Peng Chen

Jian Lin

Qian Yang

Affiliations

Soon will be listed here.

Abstract

Importance: The potential of surfactin as a microbial surfactant extends beyond its surfactant properties, impacting immune regulation and gut health. As the need for alternatives to traditional antibiotics continues to grow, surfactin's ability to enhance host defense mechanisms against common pathogens without directly targeting them with antibiotics offers a strategic advantage. Understanding how surfactin shapes the immune landscape and the gut microbiome can inform innovative interventions against immunosuppression and intestinal impairment, particularly in contexts such as cyclophosphamide-induced toxicity.

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