Short-Term Visual and Refractive Outcomes of Single-Step Transepithelial Photorefractive Keratectomy with Amaris 750S and SmartSurf in Myopia and Astigmatism: A 6-Month Follow-Up Study

Overview

Journal Life (Basel)

Specialty Biology

Date 2024 Oct 26

PMID 39459588

Authors

Daiana-Andreea Margarit

Horia Tudor Stanca

Valeria Mocanu

Mihnea Munteanu

Suta Marius

Suta Gheorghita

Affiliations

Soon will be listed here.

Abstract

Background: Single-step transepithelial photorefractive keratectomy (TPRK) is a modern refractive surgery technique that offers a no-touch approach for correcting myopia and astigmatism. This study aims to evaluate the short-term visual and refractive outcomes of TPRK in patients with myopia and astigmatism over a 6-month follow-up period.

Methods: This retrospective cohort study included patients who underwent single-step TPRK using the Amaris 750S laser platform with SmartSurf and SmartPulse technologies, targeting a plano refraction. Procedures were performed with aspheric, non-wavefront-guided profiles, and outcomes were assessed postoperatively.

Results: 96% of eyes achieved 20/20 or better uncorrected distance visual acuity (UDVA), with 98% reaching 20/25 or better, and 100% achieving 20/32 or better. UDVA was the same or better than preoperative corrected distance visual acuity (CDVA) in 96% of eyes, and no eyes lost two or more Snellen lines. Refractive outcomes showed strong precision, with 93% of eyes within ±1.00 D of the target. Astigmatism correction was accurate, with 100% of eyes having ≤1.00 D of astigmatism, and 80% achieving a precise astigmatism angle of error between -5° and 5°.

Conclusion: Single-step TPRK with SmartSurf and SmartPulse technologies provides highly effective and predictable visual and refractive outcomes for myopia and astigmatism. The procedure consistently delivers precise corrections with minimal complications, making it a reliable option for refractive surgery.

References

Charpentier S, Keilani C, Marechal M, Friang C, de Faria A, Froussart-Maille F . Corneal haze post photorefractive keratectomy. J Fr Ophtalmol. 2021; 44(9):1425-1438. DOI: 10.1016/j.jfo.2021.05.006. View

Way C, Elghobaier M, Nanavaty M . Transepithelial Photorefractive Keratectomy-Review. Vision (Basel). 2024; 8(1). PMC: 10974391. DOI: 10.3390/vision8010016. View

Ghanem R, Piccinini A, Ghanem V . Photorefractive Keratectomy With Mitomycin C in Meesmann's Epithelial Corneal Dystrophy. J Refract Surg. 2017; 33(1):53-55. DOI: 10.3928/1081597X-20161027-03. View

Reinstein D, Waring 3rd G . Graphic reporting of outcomes of refractive surgery. J Refract Surg. 2009; 25(11):975-8. DOI: 10.3928/1081597X-20091016-01. View

Sanchez-Gonzalez J, Alonso-Aliste F, Borroni D, Amian-Cordero J, De-Hita-Cantalejo C, Capote-Puente R . Plasma Rich in Growth Factors (PRGF) in Transepithelial Photorefractive Keratectomy (TPRK). J Clin Med. 2021; 10(9). PMC: 8124326. DOI: 10.3390/jcm10091939. View

Al-Mohaimeed M . Factors affecting single-step transepithelial photorefractive keratectomy outcome in the treatment of mild, moderate, and high myopia: a cohort study. Int J Ophthalmol. 2022; 15(5):786-792. PMC: 9091891. DOI: 10.18240/ijo.2022.05.15. View

Kim T, Alio Del Barrio J, Wilkins M, Cochener B, Ang M . Refractive surgery. Lancet. 2019; 393(10185):2085-2098. DOI: 10.1016/S0140-6736(18)33209-4. View

Medeiros C, Marino G, Lassance L, Thangavadivel S, Santhiago M, Wilson S . The Impact of Photorefractive Keratectomy and Mitomycin C on Corneal Nerves and Their Regeneration. J Refract Surg. 2018; 34(12):790-798. PMC: 6360090. DOI: 10.3928/1081597X-20181112-01. View

Fay J, Juthani V . Current trends in pain management after photorefractive and phototherapeutic keratectomy. Curr Opin Ophthalmol. 2015; 26(4):255-9. DOI: 10.1097/ICU.0000000000000170. View

10.

Adib-Moghaddam S, Soleyman-Jahi S, Moghaddam A, Hoorshad N, Tefagh G, Haydar A . Efficacy and safety of transepithelial photorefractive keratectomy. J Cataract Refract Surg. 2018; 44(10):1267-1279. DOI: 10.1016/j.jcrs.2018.07.021. View

11.

Bakhsh A, Elwan S, Chaudhry A, El-Atris T, Al-Howish T . Comparison between Transepithelial Photorefractive Keratectomy versus Alcohol-Assisted Photorefractive Keratectomy in Correction of Myopia and Myopic Astigmatism. J Ophthalmol. 2018; 2018:5376235. PMC: 6260527. DOI: 10.1155/2018/5376235. View

12.

Li H, Zhang J, Shao T, Wang H, Liu S, Long K . Two-year stability of posterior corneal surface after transepithelial photorefractive keratectomy with a residual stromal thickness less than 350 μm. Graefes Arch Clin Exp Ophthalmol. 2022; 261(3):857-865. DOI: 10.1007/s00417-022-05814-3. View

13.

Zhang J, Feng Q, Ding W, Peng Y, Long K . Comparison of clinical results between trans-PRK and femtosecond LASIK for correction of high myopia. BMC Ophthalmol. 2020; 20(1):243. PMC: 7304146. DOI: 10.1186/s12886-020-01515-9. View

14.

Dupps Jr W, Kohnen T, Mamalis N, Rosen E, Koch D, Obstbaum S . Standardized graphs and terms for refractive surgery results. J Cataract Refract Surg. 2010; 37(1):1-3. DOI: 10.1016/j.jcrs.2010.11.010. View

15.

de Ortueta D, von Ruden D, Verma S, Magnago T, Arba-Mosquera S . Transepithelial Photorefractive Keratectomy in Moderate to High Astigmatism With a Non-wavefront-Guided Aberration-Neutral Ablation Profile. J Refract Surg. 2018; 34(7):466-474. DOI: 10.3928/1081597X-20180402-04. View

16.

Hashemi H, Pakbin M, Pakravan M, Fotouhi A, Jafarzadehpur E, Aghamirsalim M . Effect of Short Versus Long-Term Steroid on Corneal Haze After Photorefractive Keratectomy: A Randomized, Double-Masked Clinical Trial. Am J Ophthalmol. 2021; 235:211-220. DOI: 10.1016/j.ajo.2021.09.028. View

17.

Zarei-Ghanavati S, Heravian Shandiz J, Abrishami M, Karimpour M . Comparison of mechanical debridement and trans-epithelial myopic photorefractive keratectomy: A contralateral eye study. J Curr Ophthalmol. 2019; 31(2):135-141. PMC: 6611919. DOI: 10.1016/j.joco.2019.01.003. View

18.

Luger M, Ewering T, Arba-Mosquera S . Consecutive myopia correction with transepithelial versus alcohol-assisted photorefractive keratectomy in contralateral eyes: one-year results. J Cataract Refract Surg. 2012; 38(8):1414-23. DOI: 10.1016/j.jcrs.2012.03.028. View

19.

Reinstein D, Archer T, Randleman J . JRS standard for reporting astigmatism outcomes of refractive surgery. J Refract Surg. 2014; 30(10):654-9. DOI: 10.3928/1081597X-20140903-01. View

20.

Alasmari M, Alfawaz A . Transepithelial photorefractive keratectomy to treat mild myopia. Int Ophthalmol. 2021; 41(7):2575-2583. DOI: 10.1007/s10792-021-01816-y. View