Factors Affecting Single-step Transepithelial Photorefractive Keratectomy Outcome in the Treatment of Mild, Moderate, and High Myopia: a Cohort Study

Overview

Journal Int J Ophthalmol

Specialty Ophthalmology

Date 2022 May 23

PMID 35601171

Authors

Mansour M Al-Mohaimeed

Affiliations

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Abstract

Aim: To investigate the effect of preoperative factors on visual acuity, higher-order aberrations (HOAs), and index of success for spherical change (S.IOS) after transepithelial photorefractive keratectomy (t-PRK) for treating different grades of myopia.

Methods: This was a retrospective one-armed cohort study where patients with high, moderate, or mild myopia treated with single-step t-PRK using Amaris 500 Hz excimer laser were evaluated for visual acuity, refractive status, corneal topography, HOAs, S.IOS, and mean efficiency and safety index before and 6mo after surgery.

Results: A total of 154 eyes of 77 patients with mild (=59), moderate (=83), and high (=12) myopia were reviewed. The efficiency and safety indices for vision recovery by single-step t-PRK were 98% and 100%, respectively. The achieved spherical equivalent (SE) was within 1 diopter (D) in 151 (98%) eyes. The median of the S.IOS was 1.18 [interquartile range (IQR) 1.0, 1.4]. The change in S.IOS was significantly correlated with age (=0.007), 6.5 mm ablation zone (Mann-Whitney test, <0.01), and mild and moderate grade of myopia (Kruskal-Wallis test, <0.001). Trefoil aberration, spherical aberration, and aberration coefficient types of HOA increased significantly (Wilcoxon test, <0.001) 6mo post-surgery. There was a significant correlation between spherical aberration and aberration coefficient HOAs by myopia grades (<0.05).

Conclusion: Single-step t-PRK has promising short-term outcomes for refractive corrections and vision improvement to treat all three grades of myopia.

Citing Articles

Short-Term Visual and Refractive Outcomes of Single-Step Transepithelial Photorefractive Keratectomy with Amaris 750S and SmartSurf in Myopia and Astigmatism: A 6-Month Follow-Up Study.

Margarit D, Stanca H, Mocanu V, Munteanu M, Marius S, Gheorghita S Life (Basel). 2024; 14(10).

PMID: 39459588 PMC: 11509222. DOI: 10.3390/life14101288.

A 6-Month Follow-Up Comparative Study of Single-Step Transepithelial Photorefractive Keratectomy (Trans-PRK) Using the StreamLight Software with and without Epithelial Thickness Customization.

Aramberri J, Lauzirika G, Illarramendi I, Mendicute J Clin Ophthalmol. 2024; 18:2831-2841.

PMID: 39398468 PMC: 11471074. DOI: 10.2147/OPTH.S487627.

Comparison of the efficacy and safety of removing bandage contact lenses on the fourth and seventh postoperative day after transepithelial photorefractive keratectomy.

Zhou H, Jin Y, Tong G, Zhao G, Wu H Heliyon. 2023; 9(10):e21129.

PMID: 37886779 PMC: 10597848. DOI: 10.1016/j.heliyon.2023.e21129.

Comment on "Factors affecting single-step transepithelial photorefractive keratectomy outcome in the treatment of mild, moderate, and high myopia: a cohort study".

Chaurasiya S, Sharma V, Agarwal P Int J Ophthalmol. 2023; 16(5):836.

PMID: 37206164 PMC: 10172083. DOI: 10.18240/ijo.2023.05.23.

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