Far-UVC Light (222 Nm) Efficiently Inactivates Clinically Significant Antibiotic-resistant Bacteria on Diverse Material Surfaces

Overview

Journal Microbiol Spectr

Specialty Microbiology

Date 2024 Oct 25

PMID 39451044

Authors

Jhen-Rong Huang

Tsai-Wen Yang

Ya-I Hsiao

Hui-Min Fan

Han-Yueh Kuo

Kuo-Hsiang Hung

Po-Yen Chen

Ching-Ting Tan

Pei-Lan Shao

Affiliations

Soon will be listed here.

Abstract

Importance: This study is crucial, providing compelling evidence on Far-ultraviolet radiation C (Far-UVC) light's efficacy against clinically significant antibiotic-resistant bacteria-a pressing issue in microbiology and infection control. Our research employs antibiotic-resistant strains from clinically isolated bacteria, emphasizing real-world relevance. Simultaneously, we assess Far-UVC light (222 nm) across diverse material surfaces commonly found in clinical settings. This dual approach ensures practical applicability and broad relevance. Our comprehensive setup and rigorous methodologies unequivocally demonstrate Far-UVC light's potency in combating antibiotic-resistant bacteria. Since 222 nm far-UVC has a disinfection capability and is harmless to mammalian cells, this dual effectiveness positions Far-UVC as a secure tool for infection control, with potential applications in healthcare settings, mitigating antibiotic-resistant bacteria spread, and reducing healthcare-associated infections.

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