Clinical Outcomes of Nonsurgical Root Canal Treatment Using NeoSealer Flo and Endosequence BC Sealer: A Retrospective Analysis with Short-term Follow-up

Overview

Journal Clin Oral Investig

Specialty Dentistry

Date 2024 Oct 15

PMID 39407050

Authors

Christian Lepure

Ryan M Walsh

Sayeed Attar

Casey L Turner

Joshua Crawford

Poorya Jalali

Affiliations

Soon will be listed here.

Abstract

Objectives: Sealers are an important component in root canal obturation to provide the seal of the root canal system. In recent years, there has been an increase in the use of hydraulic silicate sealers, commonly referred to as bioceramic sealers, due to their many advantageous properties. NeoSealer Flo (NS; Avalon Biomed USA, Houston TX) is a recently introduced premixed bioceramic sealer. There is limited evidence on its properties and clinical performance. Therefore, the purpose of this study was to evaluate the outcome of root canal treatment using NS in a sealer-based obturation technique.

Materials And Methods: The records of patients in a private practice between 2017 and 2022 were analyzed to identify both initial and retreatment cases obturated with either EndoSequence BC sealer or NS using sealer-based obturation with a minimum of one-year follow-up. Treatment outcome between NS and BC was compared with chi-square test. Logistic regression was used to identify additional prognostic factors.

Results: Six hundred and eighty-seven teeth met the inclusion criteria for the study. The success rate of cases obturated with BC was 94.9% and 96.5% for the cases obturated with NS. No statistically significant differences were found between the two sealer types. Presence of a periapical radiolucency or periapical radiolucency > 5.00 mm were statistically significant prognostic factors.

Conclusions: Endodontic treatment using BC or NS with sealer-based obturation method is a viable treatment option.

Clinical Relevance: Root canal obturation with bioceramic sealers, such as NeoSealer Flo and Endosequence BC sealer, provide favorable clinical outcomes.

References

Ng Y, Mann V, Rahbaran S, Lewsey J, Gulabivala K . Outcome of primary root canal treatment: systematic review of the literature -- Part 2. Influence of clinical factors. Int Endod J. 2007; 41(1):6-31. DOI: 10.1111/j.1365-2591.2007.01323.x. View

de Miranda Candeiro G, Campelo Correia F, Duarte M, Ribeiro-Siqueira D, Gavini G . Evaluation of radiopacity, pH, release of calcium ions, and flow of a bioceramic root canal sealer. J Endod. 2012; 38(6):842-5. DOI: 10.1016/j.joen.2012.02.029. View

Ricucci D, Grande N, Plotino G, Tay F . Histologic Response of Human Pulp and Periapical Tissues to Tricalcium Silicate-based Materials: A Series of Successfully Treated Cases. J Endod. 2019; 46(2):307-317. DOI: 10.1016/j.joen.2019.10.032. View

Giacomino C, Wealleans J, Kuhn N, Diogenes A . Comparative Biocompatibility and Osteogenic Potential of Two Bioceramic Sealers. J Endod. 2018; 45(1):51-56. DOI: 10.1016/j.joen.2018.08.007. View

Zhou H, Shen Y, Zheng W, Li L, Zheng Y, Haapasalo M . Physical properties of 5 root canal sealers. J Endod. 2013; 39(10):1281-6. DOI: 10.1016/j.joen.2013.06.012. View

Bukhari S, Karabucak B . The Antimicrobial Effect of Bioceramic Sealer on an 8-week Matured Enterococcus faecalis Biofilm Attached to Root Canal Dentinal Surface. J Endod. 2019; 45(8):1047-1052. DOI: 10.1016/j.joen.2019.04.004. View

Wang Z, Shen Y, Haapasalo M . Dentin extends the antibacterial effect of endodontic sealers against Enterococcus faecalis biofilms. J Endod. 2014; 40(4):505-8. DOI: 10.1016/j.joen.2013.10.042. View

Gandolfi M, Taddei P, Modena E, Siboni F, Prati C . Biointeractivity-related versus chemi/physisorption-related apatite precursor-forming ability of current root end filling materials. J Biomed Mater Res B Appl Biomater. 2013; 101(7):1107-23. DOI: 10.1002/jbm.b.32920. View

Reyes-Carmona J, Felippe M, Felippe W . The biomineralization ability of mineral trioxide aggregate and Portland cement on dentin enhances the push-out strength. J Endod. 2010; 36(2):286-91. DOI: 10.1016/j.joen.2009.10.009. View

10.

Cardinali F, Camilleri J . A critical review of the material properties guiding the clinician's choice of root canal sealers. Clin Oral Investig. 2023; 27(8):4147-4155. PMC: 10415471. DOI: 10.1007/s00784-023-05140-w. View

11.

Al-Haddad A, Che Ab Aziz Z . Bioceramic-Based Root Canal Sealers: A Review. Int J Biomater. 2016; 2016:9753210. PMC: 4868912. DOI: 10.1155/2016/9753210. View

12.

Chybowski E, Glickman G, Patel Y, Fleury A, Solomon E, He J . Clinical Outcome of Non-Surgical Root Canal Treatment Using a Single-cone Technique with Endosequence Bioceramic Sealer: A Retrospective Analysis. J Endod. 2018; 44(6):941-945. DOI: 10.1016/j.joen.2018.02.019. View

13.

Zamparini F, Prati C, Taddei P, Spinelli A, Di Foggia M, Gandolfi M . Chemical-Physical Properties and Bioactivity of New Premixed Calcium Silicate-Bioceramic Root Canal Sealers. Int J Mol Sci. 2022; 23(22). PMC: 9692705. DOI: 10.3390/ijms232213914. View

14.

Kim J, Cho S, Choi Y, Kim D, Shin S, Jung I . Clinical Efficacy of Sealer-based Obturation Using Calcium Silicate Sealers: A Randomized Clinical Trial. J Endod. 2021; 48(2):144-151. DOI: 10.1016/j.joen.2021.11.011. View

15.

Friedman S, Abitbol S, Lawrence H . Treatment outcome in endodontics: the Toronto Study. Phase 1: initial treatment. J Endod. 2003; 29(12):787-93. DOI: 10.1097/00004770-200312000-00001. View

16.

KEREKES K, Tronstad L . Long-term results of endodontic treatment performed with a standardized technique. J Endod. 1979; 5(3):83-90. DOI: 10.1016/S0099-2399(79)80154-5. View

17.

Bystrom A, Happonen R, Sjogren U, Sundqvist G . Healing of periapical lesions of pulpless teeth after endodontic treatment with controlled asepsis. Endod Dent Traumatol. 1987; 3(2):58-63. DOI: 10.1111/j.1600-9657.1987.tb00543.x. View

18.

Orstavik D . Time-course and risk analyses of the development and healing of chronic apical periodontitis in man. Int Endod J. 1996; 29(3):150-5. DOI: 10.1111/j.1365-2591.1996.tb01361.x. View

19.

Malkondu O, Kazandag M, Kazazoglu E . A review on biodentine, a contemporary dentine replacement and repair material. Biomed Res Int. 2014; 2014:160951. PMC: 4082844. DOI: 10.1155/2014/160951. View

20.

Torabinejad M, Chivian N . Clinical applications of mineral trioxide aggregate. J Endod. 1999; 25(3):197-205. DOI: 10.1016/S0099-2399(99)80142-3. View