As a Potential Guardian Against Oral Health Diseases: A Narrative Review

Overview

Journal Nutrients

Date 2024 Sep 28

PMID 39339675

Authors

Molly H Anderson

Karima Ait-Aissa

Amal M Sahyoun

Ammaar H Abidi

Modar Kassan

Affiliations

Soon will be listed here.

Abstract

The oral microbiome is a diverse ecosystem containing a community of symbiotic, commensal, and pathogenic microorganisms. One key microorganism linked to periodontal disease (PD) is (), a Gram-negative anaerobic bacterium known to have several virulence factors that trigger inflammation and immune evasion. On the other hand, (), a symbiotic bacterium, has been recently shown to play an important role in mitigating inflammation and reducing periodontal damage. In vivo and in vitro studies have shown that decreases inflammatory mediators and improves immune responses, suggesting its role in mitigating PD and related inflammatory systemic conditions such as diabetes, hypertension, and obesity. This review discusses the anti-inflammatory effects of , its impact on periodontal health, and its potential role in managing systemic diseases. The overall aim is to elucidate how this bacterium might help reduce inflammation, improve oral health, and influence broader health outcomes.

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