Prevalence of Cardiomyopathy in Patients with Type 1 Diabetes Mellitus

Overview

Journal J Clin Med

Specialty General Medicine

Date 2024 Sep 28

PMID 39336838

Authors

Oscar Daniel Fabila-de la Cruz

Eduardo Salif Luna-Avila

Maria Del Pilar Sotelo-Gonzalez

Andres D Litardo-Mosquera

Oscar Orihuela

Aldo Ferreira-Hermosillo

Affiliations

Soon will be listed here.

Abstract

Diabetic cardiac muscle disease or diabetic cardiomyopathy (DbCM) comprises a set of myocardial lesions that are not associated with coronary atherosclerosis or high blood pressure. It is characterized by fibrosis and hypertrophy, which ultimately results in heart failure. Diastolic dysfunction (DD) has been shown to be the first manifestation of diabetic cardiomyopathy. Currently, there are few studies on the prevalence of diabetic cardiomyopathy in adult patients diagnosed with type 1 diabetes mellitus (T1D). The study included 75 adult participants who underwent an echocardiogram. Data on their comorbidities were collected from their medical records and biochemical parameters were analyzed in blood and urine samples. We found that the prevalence of DbCM in our T1D population was more than one-third (34%), which exceeded the prevalence reported in studies with adolescents and that reported in the population without diabetes. Also, we found that the probability of developing DD after 20 years of T1D diagnosis was 78%. Recommendations need to be issued in relation to diabetic cardiomyopathy to carry out secondary prevention in adult patients with T1D. More multicenter studies, which include a larger population, from different regions of the world need to be performed.

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