The Discovery and Development of GLP-1 Based Drugs That Have Revolutionized the Treatment of Obesity

Overview

Journal Proc Natl Acad Sci U S A

Specialty Science

Date 2024 Sep 19

PMID 39297680

Authors

Jeffrey M Friedman

Affiliations

Soon will be listed here.

Abstract

The 2024 Lasker~DeBakey Clinical Medical Research Award has been given to Joel Habener and Svetlana Mojsov for their discovery of a new hormone GLP-1(7-37) and to Lotte Knudsen for her role in developing sustained acting versions of this hormone as a treatment for obesity. Each of the three had a distinct set of skills that made this advance possible; Habener is an endocrinologist and molecular biologist, Mojsov is a peptide chemist, and Knudsen is a pharmaceutical scientist. Their collective efforts have done what few thought possible-the development of highly effective medicines for reducing weight. Their research has also solved a mystery that began more than a century ago.

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