Comparative Long-term Outcomes of Unicompartmental and Total Knee Arthroplasty in Knee Osteoarthritis Patients: a Systematic Review and Meta-analysis

Overview

Journal Front Surg

Specialty General Surgery

Date 2024 Sep 5

PMID 39233767

Authors

Hai Hu

Pengfei Li

Zelin Liu

Hang Lv

Xiangjun Yang

Peiran Liu

Affiliations

Soon will be listed here.

Abstract

Background: Long-term outcomes for knee osteoarthritis patients undergoing unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) remain inconclusive.

Objectives: This study aims to evaluate the long-term outcomes over five years, including Knee Society Pain Scores (KSPS), Knee Society Scores (KSS), Knee Society Function Scores (KSFS), range of motion (ROM), and survival rates-of UKA vs. TKA in knee osteoarthritis patients.

Design: Systematic review using data from randomized controlled and cohort trials, and world databases.

Data Sources: Researchers searched Medline, Embase, Cochrane Controlled Register of Trials, and ClinicalTrials.gov from January 1990 to March 2024.

Eligibility Criteria For Selecting Studies: The researchers selected studies based on adult participants with knee osteoarthritis. Eligible studies compare UKA and TKA reports on clinical or surgical outcomes, including KSPS, KSS, KSFS, ROM and survival rates, over 5 years. The researchers excluded the studies fewer than five years, or if English text was unavailable.

Results: Researchers categorized twenty-nine eligible studies into three groups: five randomized controlled trials, 11 registries and database studies, and 13 cohort studies. The analysis revealed that neither TKA nor UKA definitively outperformed the other in terms of pain (SMD (95% CI): -0.06 [-0.41, 0.28], = 90%) and KSS scores (SMD (95% CI): -0.07 [-0.23, 0.008], = 81%) over a period of five years. However, KSFS (SMD (95% CI): -0.30 [-0.43, -0.17], = 74%) and ROM (SMD (95% CI): -0.78 [-1.11, -0.46], = 92%) tended to favor UKA, and survival rate favor TKA at 5 or over 5-year follow-up periods.

Conclusions: UKA shows a trend towards better outcomes in KSFS and ROM, alongside a more favorable survival rate in TKA at the five-year and beyond follow-up periods.

Systematic Review Registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=517835, PROSPERO (CRD42024517835).

Citing Articles

Geriatric Nutritional Risk Index is a risk factor for long-term decreases in patient-reported outcome measures following total knee arthroplasty.

Kokubu Y, Kawahara S, Hamai S, Akasaki Y, Sato T, Konishi T J Exp Orthop. 2025; 12(1):e70170.

PMID: 39944723 PMC: 11815201. DOI: 10.1002/jeo2.70170.

Characterization of rectus femoris lesions in knee osteoarthritis at different stages and the effect of ultrasound-guided acupotomy.

Yu W, Liu J, Lin Z, Liu H, Zhang L, Feng X Front Physiol. 2025; 15:1496425.

PMID: 39916866 PMC: 11799896. DOI: 10.3389/fphys.2024.1496425.

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