Telluride-Based Pillar[5]arene: A Recyclable Catalyst for Alkylation Reactions in Aqueous Solution

Overview

Journal J Org Chem

Publisher American Chemical Society

Specialty Chemistry

Date 2024 Sep 5

PMID 39233358

Authors

Patrick C Nobre

Pamella Cordeiro

Ingrid C Chipoline

Victor Menezes

Kaila V S Santos

Alix Y Bastidas Angel

Eduardo E Alberto

Vanessa Nascimento

Affiliations

Soon will be listed here.

Abstract

The syntheses of previously unknown sulfide- and telluride-pillar[]arenes are reported here. These macrocycles, among others, were tested as catalysts for alkylation reactions in aqueous solutions. Telluride-pillar[5]arene () showed the best performance, emulating the behavior of the methyltransferase enzyme cofactor -adenosyl-l-methionine. Using 1.0 mol % of , benzyl bromides reacted with NaCN/NaN in water, yielding organic nitriles/azides. The catalyst was recycled and efficiently reused for up to six cycles. H NMR experiments indicate a possible interaction between the substrate and 's cavity.

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