Non-traditional Small Companion Mammals in Spain As Reservoirs of Antimicrobial-resistant

Overview

Journal Front Vet Sci

Specialty Veterinary Medicine

Date 2024 Aug 26

PMID 39183750

Authors

Ana Marco-Fuertes

Clara Marin

Jose Villora-Gonzalez

Concepcion Gimeno-Cardona

Violeta Artal-Munoz

Santiago Vega

Laura Montoro-Dasi

Affiliations

Soon will be listed here.

Abstract

Introduction: The increasing prevalence of antimicrobial resistance (AMR) and multidrug resistance (MDR) in microorganisms poses a significant concern in both human and veterinary medicine. Non-traditional companion animals (NTCAs), particularly popular amongst households with children, play a crucial role in AMR epidemiology due to their rising population. Indeed, it is known that some of these animals may act as reservoirs of zoonotic pathogens and thus be able to spread and transmit them to family members, along with their AMR, through their shared environment. It is therefore imperative to address this concern with the involvement of human, animal and environmental health professionals. This pilot study aimed to assess the prevalence and AMR patterns of spp. strains obtained from commensal mucosal and skin infection samples in NTC small mammals, with a focus on strains like methicillin-resistant spp. (MRS) that are critical in public health.

Methods: For this purpose, 81 animals of different small mammal species were sampled, assessing antimicrobial susceptibility to 27 relevant antimicrobial agents (AMAs) in human health using minimum inhibitory concentration assays, and interpreting them according to EUCAST and CLSI guidelines. The isolated i strains were identified by MALDI-TOF, with the predominant species being and .

Results And Discussion: Including all strains isolated, AMR was observed against all 27 AMAs, including six last-resort AMAs in human medicine. Additionally, over 85% of the strains exhibited MDR. These findings underscore the need to monitor AMR and MDR trends in companion animals and emphasise the potential role of NTCAs in spreading resistance to humans, other animals, and their shared environment, calling for a comprehensive "One Health" approach.

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