Virulence Factors in Coagulase-Negative Staphylococci

Overview

Journal Pathogens

Date 2021 Feb 9

PMID 33557202

Citations 58

Authors

Angela Franca

Vania Gaio

Nathalie Lopes

Luis D R Melo

Affiliations

Soon will be listed here.

Abstract

Coagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-associated facilities, being , and, more recently, , the most clinically relevant species. Despite being less virulent than the well-studied pathogen , the number of CoNS strains sequenced is constantly increasing and, with that, the number of virulence factors identified in those strains. In this regard, biofilm formation is considered the most important. Besides virulence factors, the presence of several antibiotic-resistance genes identified in CoNS is worrisome and makes treatment very challenging. In this review, we analyzed the different aspects involved in CoNS virulence and their impact on health and food.

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