A Bibliometric Analysis of Global Research on Microbial Immune Microenvironment in Melanoma from 2012 to 2022

Overview

Journal Skin Res Technol

Specialty Biomedical Engineering

Date 2024 Aug 21

PMID 39167029

Authors

Lin Sun

Jianghui Ying

Rong Guo

Lingling Jia

Hongyi Zhang

Affiliations

Soon will be listed here.

Abstract

Background: Melanoma is an aggressive malignancy primarily impacting the skin, mucous membranes, and pigment epithelium. The tumor microbial microenvironment encompasses both the microorganisms inhabiting the tumor vicinity and the environmental factors influencing their interactions. Emerging evidence highlights the pivotal role of the microbial immune microenvironment in melanoma.

Methods: We conducted an extensive review of scholarly works published from 2012 to 2022, utilizing The Web of Science Core Collection. Subsequently, we employed analytical tools such as VOSviewer, CiteSpace, and the R programming language to scrutinize prevailing research patterns within this domain.

Results: A sum of 513 articles were pinpointed, with notable input coming from the United States and China. Harvard University stood out as the top-contributing institution, while the journal Science received the most citations. Current research within this sphere chiefly focuses on two principal domains: the gut microbiota and the PD-L1 pathway concerning melanoma treatment.

Conclusion: The study offers an extensive analysis and overview of the worldwide research landscape concerning the immune microenvironment with a focus on microbes in melanoma. It underscores the promising prospects for harnessing the microbial immune microenvironment's potential in melanoma. These findings furnish valuable insights and guidance for advancing scientific inquiry and refining clinical approaches within this dynamic field.

Citing Articles

The Skin Microbiome: A New Key Player in Melanoma, From Onset to Metastatic Stage.

Lorphelin J, Dompmartin A, Dreno B Pigment Cell Melanoma Res. 2025; 38(2):e13224.

PMID: 40016867 PMC: 11868406. DOI: 10.1111/pcmr.13224.

Extract Ameliorates Melanoma Cell Proliferation and Invasion into Mouse Lungs by Suppressing PAX3 Expression.

Hiramoto K, Oikawa H Int J Mol Sci. 2024; 25(23).

PMID: 39684511 PMC: 11640897. DOI: 10.3390/ijms252312800.

Emerging trends and research hotspots in the relationship between mast cells and atopic dermatitis based on the literature from 2001 to 2024: A bibliometric and visualized analysis.

Zuo W, Yue Z, Xu S, Sun C, Zou X, Ma J Skin Res Technol. 2024; 30(9):e70053.

PMID: 39234634 PMC: 11375331. DOI: 10.1111/srt.70053.

A bibliometric analysis of global research on microbial immune microenvironment in melanoma from 2012 to 2022.

Sun L, Ying J, Guo R, Jia L, Zhang H Skin Res Technol. 2024; 30(8):e70017.

PMID: 39167029 PMC: 11337907. DOI: 10.1111/srt.70017.

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